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The extra chromosome 21 affects almost every organ system and results in a wide spectrum of phenotypic consequences.
Congenital heart defects - Almost half of affected patients have congenital Heart disease, including ventricular septal defect and atrioventricular canal defect.
Abnormal physiologic functioning affects thyroid metabolism and intestinal malabsorption.
There is an increased risk of obesity.
Frequent infections are presumably due to impaired immune responses, and the incidence of autoimmunity, including hypothyroidism and rare Hashimoto thyroiditis, are increased.
About 5% of patients with Down syndrome have gastrointestinal (GI) manifestations, includind duodenal atresia, hirschsprung disease, and celiac disease. Many patients with trisomy 21 have otorhinolaryngologic manifestations, including hearing loss and recurrent ear infections. About 60% of patients have ophthalmic manifestations.
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∙ 11y ago
Wiki User
∙ 12y agoChromosomes
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What is the genetic disorder for having three 21 chromosomes?
down syndrome
Would parents pass down syndrome to their future children?
No. Parents who have a child with Down syndrome do not have an increased chance in having another child with Down syndrome. Everyone has the same chance of having a child with Down syndrome, 1%.
What race does Down syndrome affect?
Down Syndrome affects all races. Down Syndrome does not affect all races evenly its affects Mexicans more than any one else. Hispanics have larger numbers of live births suffering from Down Syndrome because they do not terminate their DS pregnancies, like other races do.
Causes Down Syndrome?
Having an extra copy of chromosome 21. You are supposed to have 2; when you have 3 (trisomy 21), Down's Syndrome is the result.
What is a disease caused by having too many chromosomes?
down syndrome
Why can't you have a driver's license if you have down syndrome?
People with Down Syndrome CAN have a driver's license. Many people who live with Down Syndrome have a driver's license, and are perfectly fine drivers. Down Syndrome is not a disease, and people do not "suffer" from Down Syndrome. Down Syndrome does not prevent anybody from safely driving, going to college, owning a house, being married, having children, operating a business, or anything else.
What are the chances that a sibling of a Down syndrome brother will have a baby with Down syndrome?
After having one child with Down Syndrome, the likelihood of having another is about one percent. If the first child's Down Syndrome is due to translocation trisomy 21, the likelihood of another Down Syndrome child increases. As far as researchers know at this point, Down Syndrome is not attributed to the parents' behavior prior and/or during pregnancy or any environmental factors. The incidence of Down Syndrome does rise if the mother is older than 35, but it does not account for a large number of Down Syndrome children. Since more women are having children at ages younger than 35, then number of babies born with the syndrome is higher in younger age groups.
Can a person with Down syndrome have normal kids?
That depends. Men with Down syndrome have been shown to be sterile, while women with Down syndrome are capable of carrying a child, with 50% likelihood that the child will be born with Down syndrome.
What community is most at risk for down syndrome?
Older women who give birth have a much higher chance of having a baby with Down syndrome than do other women.
What are the statistics of a mother having a child with down syndrome?
For the United States, estimated as the fraction of people in the population with the syndrome, ~1/5500.
What are the similarities and differences between Down syndrome and Turner syndrome?
Down syndrome is caused by an extra or part of an extra 21st chromosome while Turner syndrome is caused by an absence in one or part of the sex(X) chromosome.Down syndrome can occur in both male and femalewhile Turner syndrome only occurs in female.People with Down syndrome tend to have a lower than average cognitive ability.Both Down syndrome and Turner syndrome are at higher risk for having medical conditions such as heart problems.
What is the disorder caused by having an abnormality on chromosome 21?
Down's Syndrome or trisomy 21.
