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Assuming you mean "ligases," a ligase is an enzyme that catalyzes the formation of a chemical bond between two smaller molecules to form a larger one. The most common example is DNA ligase, which joins DNA strands together. This occurs on the lagging strand of DNA synthesis where synthesis occurs in short Okazaki fragments. These fragments are joined together by ligase, which acts to "seal the nicks" forming one continuous strand of DNA.

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Q: What type of chemical reactions do ligasis catalyze?
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