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Is histoplasmosis a fungal disease?
Histoplasmosis is a fungal infection caused by inhaling spores of Histoplasma Capsulatum.
What forms of histoplasmosis are potentially fatal?
Chronic histoplasmosis affects the lungs and can be fatal. Disseminated histoplasmosis affects many organ systems in the body and is often fatal
What has the author T F Schlaegel written?
T. F. Schlaegel has written: 'Ocular histoplasmosis' -- subject(s): Eye Diseases, Histoplasmosis, Ocular histoplasmosis 'Essentials of uveitis' -- subject(s): Uveitis
What is the treatment for chronic histoplasmosis?
Patients with an intact immune system who develop chronic histoplasmosis are treated with the drug ketoconazole (Nizoral) or amphotericin B (Fungizone).
What are granulomatous calcifications in the spleen?
Some ancestral diseases can affect the bodyÃ?s resistance to illness; one of these ailments is chronic granulomatous disease. If you have this disease in your spleen it can lead to continuing serious contamination.
Who discovered Histoplasmosis treatment?
Samuel Taylor darling
What are the symptoms of chronic histoplasmosis?
Symptoms of chronic histoplasmosis resemble those of tuberculosis. Cavities form in the lung tissue, parts of the lung may collapse, and the lungs fill with fluid
When you see Ohio river valley you should think?
Histoplasmosis
What are the symptoms of disseminated histoplasmosis?
a worsening of those found in chronic histoplasmosis, as well as weight loss, diarrhea, the development of open sores in the mouth and nose, and enlargement of the spleen, liver, and adrenal gland
Histoplasmosis - chronic pulmonary?
DefinitionChronic pulmonary histoplasmosis is a long-term respiratory infection caused by breathing the spores of the fungus, Histoplasma capsulatum.See also:Acute pulmonary histoplasmosisDisseminated histoplasmosisSkin lesion of histoplasmosisAlternative NamesChronic cavitary histoplasmosisCauses, incidence, and risk factorsHistoplasma capsulatum is a fungus found in the soil of the central and eastern United States (especially Mississippi and Ohio river valleys), eastern Canada, Mexico, Central America, and South America.The infection occurs when a person breathes in the reproducing parts of the fungus, called spores. Those who have a healthy immune system usually do not have symptoms, or only mild ones.This "acute" infection does not last, but can leave a person with small scars (granulomas). These scars can be difficult to distinguish from tumors in the lung.However, the infection can cause severe illness right away, or redevelop years after the first exposure, if a person's immune system is weakened by:CancerChemotherapyImmune-suppressing drugsHIV infectionRisk factors for chronic pulmonary histoplasmosis include:Living in or traveling to central or eastern United StatesExposure to soil or particles contaminated with droppings of chickens, bats, or blackbirdsPre-existing COPDWeakened immune system, such as in people who have AIDSSymptomsChillsCough that brings up blood, mucus, or pusFeverShortness of breathUnintentional weight lossSigns and testsTests that may be used to diagnose chronic pulmonary histoplasmosis include:Biopsy of infected tissue, such as open lung biopsyBronchoscopy with transbronchial biopsy or bronchoalveolar lavageCBCChest CT scanChest x-rayHistoplasma complement fixation titerHistoplasma urinary antigen test (positive only if the person also has disseminated histoplasmosis)Immunodiffusion testSputum cultureand stainTreatmentThe doctor will prescribe antifungal medications to control the infection within the lung. These medications must be taken for 1 to 2 years.Expectations (prognosis)The infection usually goes away with antifungal medication, but scarring inside the lung often remains. Histoplasmosis is unusual enough that if you develop it, your health care provider should check to find out whether another disease is weakening your immune system.Often, those who have had chronic pulmonary histoplasmosis must follow up with their doctor, who will check for signs of relapse.In rare cases, a pulmonary histoplasmosis infection can spread through the blood to other organs. This is called disseminated histoplasmosis. People who have a suppressed immune system and very young children are more likely to develop this condition. If this occurs, the prognosis is less favorable.ComplicationsArthritisDisseminated histoplasmosisLung scarring (fibrosis)PericarditisRespiratory insufficiencyPatients who breathe in a large amount of fungus can develop a severe and potentially deadly and sudden type of lung infection.Calling your health care providerCall for an appointment with your health care provider if you develop symptoms of chronic pulmonary histoplasmosis.Call your health care provider if your symptoms continue despite treatment, or if you have breathing difficulty or symptoms of disseminated histoplasmosis.PreventionBe aware of your surroundings, especially if you are in a weakened state from another medical condition, or from immune-suppressing medications.ReferencesKauffman CA. Histoplasmosis. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 353.What LJ, Freifeld AG, Kleiman MB, Baddley JW, McKinsey DS, Loyd JE, Kauffman CA. Clinical practice guidelines for the management of patients with histoplasmosis: 2007 update by the Infectious Diseases Society of America. Clin Infect Dis, 2007;45(7):807-825.
In what type of infection is the host cell not destroyed?
Lysogenetic infection
What is the type of infection in which the host cell bursts and is destroyed?
lytic infection
