The Santa Fe Trail.
It didn't go through hostile territory.
becknells route came to be known as the santa fe trail. the trail started near independence, Missouri, and crossed the prairies to the Arkansas river.
The Santa Fe Trail
William Becknell was a trader and merchant. He is best known for establishing the Santa Fe Trail, a major commercial route between Missouri and Santa Fe, New Mexico, in the early 19th century.
In 1821, Captain William Becknell left Franklin Missouri to trade with New Mexico. His route became known as the Santa Fe Trail.
It didn't go through hostile territory.
His route was from Cuba to Mexico
Route 66 goes through Albuquerque, New Mexico.
route 66
The Camino Real de Tierra Adentro went from Mexico City to Santa Fe, New Mexico. It was also known as the Royal Inland Road.
He is credited with opening the Santa Fe Trailin 1821, which became an early major transportation route through central North America that connected Independence, Missouri with Santa Fe, New Mexico.
Yes, through the Isthmus of Tehuantepec on southern Mexico, it could. Prior to the opening of the Panama Canal, it was a major shipping route known as the Tehuantepec Route and at various times throughout the years, an artificial canal such as the one found in Panama has been proposed.