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All ferret have seasonal coat changes, and in unaltered ferrets it coincides with their reproduction cycles as they are seasonal breeders. Female ferrets seasonal coat change occurs five or six weeks after the beginning of estrus. Seasonal hair loss in unaltered ferrets are more pronounced as compared to altered ferrets. advice from other contributors:

Well, if they are pregnant, they mated with male ferrets. They are not losing their hair. Female ferrets, when they are pregnant, will pull out their hair to make a nest for their babies. Good luck!

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Q: What would cause hair loss of your two 1 yr old ferrets that are both pregnant?
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