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When acetylcholine diffuses across the synaptic cleft and binds to receptors on the folded sarcolemma it initaly causes what channels to open in the sarcolemma?
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∙ 9y ago
Chemically gated Na+ ions.
Wiki User
∙ 9y ago
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When acetylcholine diffuses across syaptic cleft?
Like any other neurotransmitter, acetylcholine will attach itself to active sites on the dendrite, thus triggering the opening of sodium gates of the next neuron. Once that's done, the acetylcholine either breaks down or is absorbed back into the cell it originated from.
What is the name of the cell that releases the neurotransmitters?
Exocytosis. As a result of the influx of Calcium ions, the synaptic vesicles transport the neurotransmitter Ach (Acetylcholine) to the presynaptic membrane, the vesicles fuse to the membrane, and the neurotransmiffer, Ach, diffuses. Once the neurotransmitters cross the synaptic cleft, they bind to the receptors on the post synaptic membrane. Hope it helps a bit.
When the what reaches the end of the axon the neurotransmitter is released?
When the _____________reaches the ends of the axon the neurotransmitter is released and it diffuses to the muscle cell membrane to combine with receptors there?Sarcolemma
When an electrical impluse travels along a motor neuron and arrives at a neuromuscular junction what happens?
Calcium enters through the voltage-gate and triggers the release of transmitter. " the entry of calcium through voltage-gated calcium channels causes synaptic vesicles to fuse with the presynaptic plasma membrane and release the neurotransmitter acetylcholine into the synaptic cleft. Acetylcholine diffuses across the cleft and binds to muscle acetylcholine receptors, causing depolarization and an action potential that travels throughout the length of the muscle cell triggering muscle contraction. "
What is the presynaptic knob ca2?
Your question isn't very clear.... Presynaptic knob is the neurone before the synapse. Postsynaptic knob is the neurone after the synapse. Calcium ions diffuse into the presynaptic knob down their concentration gradient when an impulse arrives at the presynaptic knob. This causes the vesicles to move towards the presynaptic membrane and fuse with it. This releases the neurotransmitter (e.g. Ach). The Ach diffuses down their concentration gradient in the synaptic cleft then binds with receptors on the post synaptic membrane. This binding causes the Na+ ion channels to open, and the influx of Na+ ions causes depolarisation, and a new action potential in the postsynaptic knob. Then the acetate and choline diffuses back into the presynaptic membrane and is recombined using ATP.
Describe the interaction of acetylcholine and calcium ions in stimulating muscle contraction?
The acetylcholine diffuses across the synapse and binds to and activates nicotinic acetylcholine receptors on the motor end plate of the muscle cell. Activation of the nicotinic receptor opens its intrinsic sodium/potassium channel, causing sodium to rush in and potassium to trickle out.
Which of these junctions represents the connection between the tip of a neuron and a skeletal muscle cell from which Acetylcholine diffuses?
Neuromuscular
What is the normal sequence of events that occur during synaptic transmission at a motor end plate?
1. Nerve impulse reaches synaptic terminal. 2. Synaptic vesicles move to and merge with the presynaptic cell membrane of the motor neuron. 3. Acetylcholine is released into and diffuses across the synaptic cleft. 4. Acetylcholine binds to receptors on the postsynaptic cell membrane of the muscle fiber.
When acetylcholine diffuses across syaptic cleft?
Like any other neurotransmitter, acetylcholine will attach itself to active sites on the dendrite, thus triggering the opening of sodium gates of the next neuron. Once that's done, the acetylcholine either breaks down or is absorbed back into the cell it originated from.
What reaches the end of the axon when the neurotransmitter is released and diffuses to the muscle membrane to combine with receptors there?
nerve impulse
What is the name of the cell that releases the neurotransmitters?
Exocytosis. As a result of the influx of Calcium ions, the synaptic vesicles transport the neurotransmitter Ach (Acetylcholine) to the presynaptic membrane, the vesicles fuse to the membrane, and the neurotransmiffer, Ach, diffuses. Once the neurotransmitters cross the synaptic cleft, they bind to the receptors on the post synaptic membrane. Hope it helps a bit.
What is the effect of acetylcholine affect sphincter muscles?
During Parasympathetic action when acetlcholine is released in the sphincter muscles then the M3 muscarinic receptors stimulate Gq protein and this in turn activate Phospholipase C (PLC). PLC then cleaves the phospholipid. In the process, phosphatidylinositol 4,5-bisphosphate (PIP2) is cleaved into diacyl glycerol (DAG) and inositol 1,4,5-triphosphate (IP3). DAG remains bound to the membrane and IP3 is released as a soluble structure in the cytosol. IP3 then diffuses through the cytosol to bind to IP3 receptors, particularly the calcium channels in the endoplasmic reticulum (ER). These channels are specific to calcium and allow only the passage of calcium to move through. This causes the cytosolic concentration of calcium to increase and cause the cascade of contractile machinery and the spinchter will contract and tighten up.
Contraction mechanism in a skeletal muscle cell?
ACH is released at the end-plate potential. ACH diffuses into the sarcolemma, attaches to the receptors in the motor end plate and causes a change in the ions permeability that creates graded depolarization of the end-plate potential. Basically, it attaches to the receptors in the motor-end plate and creates the beginning process of triggering muscle contractions.
When the what reaches the end of the axon the neurotransmitter is released?
When the _____________reaches the ends of the axon the neurotransmitter is released and it diffuses to the muscle cell membrane to combine with receptors there?Sarcolemma
When an electrical impluse travels along a motor neuron and arrives at a neuromuscular junction what happens?
Calcium enters through the voltage-gate and triggers the release of transmitter. " the entry of calcium through voltage-gated calcium channels causes synaptic vesicles to fuse with the presynaptic plasma membrane and release the neurotransmitter acetylcholine into the synaptic cleft. Acetylcholine diffuses across the cleft and binds to muscle acetylcholine receptors, causing depolarization and an action potential that travels throughout the length of the muscle cell triggering muscle contraction. "
What opens first in response to a threshold stimulus?
The activation gates of voltage-gated Na+ channels open, and Na+ diffuses into the cytoplasm.
What Neurotransmitter diffuses across a synapse to a muscle cell?
It varies: In the somatic system (skeletal muscle) and parasympathetic branch of the autonomous nervous system (smooth & cardiac muscle) it is usually acetylcholine. In the sympathetic branch of the autonomous nervous system (smooth & cardiac muscle) it is usually norepinephrine (also called noradrenaline). There are exceptions, but this is the general rule.
