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If ion pumps open to hyperpolarize the neuron (chloride ions flowing into the neuron) elsewhere, leading to a net polarization/hyperpolarization, then the action potential will not be created.In order for the AP to be induced, a NET depolarization (influx of cations) must be created above the membrane threshold.

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Q: When under what conditions will a local depolarization not lead to the action potential?
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