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There are six(6) spark plugs to require to change for the IS300. Not as easy to change.
The 2001 Lexus IS300 uses a 2JZ-GE inline-6 Toyota engine, and has 6 spark plugs.
They are located top center of the engine under the cowl packs (black things inside the v)
http://my.is/forums/f67/is300-changing-spark-plugs-340989/
the spark plugs are located under the cover, you must unscrew the Lexus symbol and the 3 other screws at the bottom and the 3 of the spark plugs are in front top, the other 3, back top
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You have to remove the panel on the valve covers, 4 bolts, and under them are the plugs.
how would you go about changing the spark plugs in a 1999 Lexus ES 300?
2006 Lexus gs300 awd check engine on after spark plugs replaced
the answer is elsewhere on this site. it appears that 3 of the plugs are on the back of the engine and you have to jack up the car to get to them....
Change spark plugs on 1999 Lexus GS300?