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I am not an expert in this field, but we did study psychiatric disorders recently in my nursing classes. The neurotransmitter serotonin controls mood and sleep (among other things), and when you decrease its levels (or if uptake is blocked), people end up with clinical depression. Antidepressants work to increase serotonin (or increase its uptake). Also, GABA (gamma-Aminobutyric acid) is an inhibitory neurotransmitter that regulates excitability in the nervous system. So if there is too little GABA present, the hormones that cause excitability run wild and you end up with anxiety (overstimulation). Anxiolytics (anti-anxiety meds) work to increase GABA, which inhibits that excitabililty and slows those anxious feelings.

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Q: Which 'neurotransmitters' excite energy and inhibit lethargy?
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Inhibit it by hyper polarizing the membrane or excite it by bringing the voltage closer to the threshold potential.


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