There is no official listing for a US city with the nickname A-town. However, Atlanta in the state of Georgia is nicknamed "the big A" which is similar to A-town.
As of June 2014, no U.S. President was nicknamed "Big Bill." William Howard Taft was nicknamed "Big Chief" and "Big Lub."
Detroit
New Orleans is known as the Big Easy. AS New York is to Big Apple, and Chicago is known as windy city.
Detroit.
Detroit, MI
New OrleansThe Big Easycrescent city
Denver, Colorado.
Pittsburgh, Pennsylvania.
Las Vegas
The mile high city is Denver, Colorado.
City of Hope is the title of a 1991 film. It takes place in the fictitious city of Hudson City, New Jersey.