0
Which cells of the stomach secretes hydrochloride acid and intrinsic factor?
Wiki User
∙ 9y agoWant this question answered?
Be notified when an answer is posted
Add your answer:
Earn +20 pts
How do you use resolution factor in HPLC?
resolution factor
The factor in an experiment that is changed on purpose?
the factor an experiment that is changed on purpose
Schilling test?
DefinitionThe Schilling test is used to determine whether the body absorbs vitamin B12normally.Alternative NamesVitamin B12 absorption testHow the test is performedThis test may be performed in four different stages to find the cause of low vitamin B12 levels.Stage I: You will get two doses of vitamin B12 (cobalamin). You will take a small, first dose (a radioactive form of B12) by mouth. You will a second, larger dose by a shot 1 hour later. You will need to collect your urine over the next 24 hours, and deliver it to a lab or your doctor's office. The urine will be checked to see if you are absorbing vitamin B12 normally. For information on collecting the urine sample, see: 24-hour urine collectionIf Stage I is abnormal, Stage II may be done 3 - 7 days later.Stage II: You are given radioactive B12 along with intrinsic factor. Intrinsic factor is a protein produced by cells in the stomach lining. The body needs it so the intestines can absorb vitamin B12 efficiently.Stage II of the test can tell whether low vitamin B12 levels are caused by problems in the stomach that prevent it from producing intrinsic factor.If a Stage II test is abnormal, a Stage III test is performed.Stage III: This test is done after you have taken antibiotics for 2 weeks. It can tell whether abnormal bacterial growth has caused the low vitamin B12 levels.Stage IV: This test determines whether low vitamin B12 levels are caused by problems with the pancreas. With this test, you will take pancreatic enzymes for three days, followed by a radioactive dose of vitamin B12.How to prepare for the testDo not eat for 8 hours before starting the test, then eat normally for the next 24 hours. You can drink water.The health care provider may ask you to stop taking drugs that can affect the test.You cannot have intramuscular injection B12 within 3 days before the test.How the test will feelThe injection of vitamin B12 may sting.Why the test is performedThe Schilling test is performed to check vitamin B12 absorption and to evaluate patients for pernicious anemia.Additional conditions under which the test may be performed:Anemia of B12 deficiencyBlind loop syndromeMegaloblastic anemiaNormal ValuesUrinating 8 - 40% of the radioactive vitamin B12 within 24 hours is normal.Note: Normal value ranges may vary slightly among different laboratories. Talk to your doctor about the meaning of your specific test results.What abnormal results meanLow vitamin B12 levels can cause megoblastic anemia.If there is a problem with the stomach's ability to make intrinsic factor, Stage I of the test will be abnormal and Stage II will be normal.Both the Stage I and II Schilling tests will be abnormal in people who have problems absorbing vitamin B12 and intrinsic factor in the small intestine.Abnormal results may be due:Biliary diseaseCeliac disease (sprue)Crohn's diseaseLiver diseasePancreatic diseaseWhat the risks areLocal reaction to vitamin injectionNauseaFeeling lightheadedReferencesAntony AC. Megaloblastic anemias. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 170.Antony AC. Megaloblastic Anemias. In: Hoffman R, Benz EJ, Shattil SS, et al, eds. Hematology: Basic Principles and Practice. 5th ed. Philadelphia, Pa: Elsevier Churchill Livingstone; 2008:chap 39.
Why cant molar mass be used as a conversion factor?
It can be used as a conversion factor.
Calculating molarity and factor of HCl and Borax solutions in standidization?
Factor in hcl ?
How stomach helps in erythropoiesis?
parietal cells which can be found in gastric gland of stomach secretes intrinsic factor, which is a type of glycoprotein. this intrinsic factor, together with vitamin B12 is required for effective absorption of iron in small intestine. iron is required in erythropoiesis to produce haemoglobin. if iron absorption is low, RBC production will be affected. in summary, stomach helps in RBC production by producing intrinsic cells required in iron absorption.
Which cells produce intrinsic factor?
Intrinsic factor is produced in the fundus and body of the stomach by parietal cells that line the stomach. The purpose of intrinsic factor is so vitamin B can be absorbed in the small intestine.
What the importance of intrinsic factor?
Intrinsic factor is glycoprotein that is produced by the parietal cells of the stomach.
Aids in absorption of vitamin b12?
It is called intrinsic factor, which enables the absorption of B12. Intrinsic factor is found in the parietal cells (mucosa cells) of the stomach lining.
Why do you need intrinsic factor?
Intrinsic factor or gastric intrinsic factor is a protein produced by the stomach. It is used to absorb vitamin B12 in the small intestine. When there is a deficiency of the Intrinsic factor, there is a deficiency in the absorption of B12 into the body and this leads to pernicious anemia.
What role of the stomach is essential to life?
production of intrinsic factor
What enables absorption of b12 across small intestine wall?
Intrinsic factor, which is made in the stomach.
Which vitamin need instritic factor for stomach for absortion?
B12 is the vitamin that requires intrinsic factor for absorption. B12 is also known as cobalamin.
The most important function of the stomach and perhaps the only function that appears to be essential for life is the?
secretion of intrinsic factor
Where does the absorption of vitamin B12 occur?
The vitamin B12 is a very important nutrient; it lowers risk of stroke, heart disease, cancer, Parkinson's, and Alzheimer's disease. The vitamin begins to absorb in the mouth, in contrast to most nutrients.
How pernicious anemia cause achlorhydria?
pernicious anemia is a vitamin B12 deficiency. Vitamin B12 requires Intrinsic Factor to be reabsorbed by the ileum. Intrinsic Factor is produced by parietal cells in stomach. If there is some damage or manipulation of parietal cells, which also produce HCl, there will be less of both intrinsic factor causing B12 deficiency and HCl causing achlorhydria.
Inadequate intrinsic factor is associated with?
due to lack of b12 No HCl and intrinsic factor = pernicious anemia
