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Which cells secrete insulin

Updated: 8/10/2023
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14y ago

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<liver cells, muscles cells but not nerve cells>

You have to remember that under regular conditions the production of ATP is derived from glucose. Every cell needs ATP to function for that reason all cells in the body need glucose to function under regular conditions. Since insulin is the hormone that signals cells to take up glucose and glucose is needed to efficiently produce ATP it makes sense that virtually every cell in the body responds to insulin including nerve cells.

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11y ago
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14y ago

Insulin is produced in the pancreas and released when any of the several stimuli is detected. The stimuli include ingested protein and glucose in the blood produced from digested food. Carbohydrate can be polymers of simple sugars or the simple sugars themselves. If the carbohydrate includes glucose then that glucose will be absorbed into the blood stream and blood glucose level will begin to rise. In target cells, insulin initiates a signal transduction, which has the effect of increasing glucose uptake and storage. Finally, insulin is degraded, terminating the response.Insulin undergoes extensive posttranslational modification along the production pathway. Production and secretion are largely independent; prepared insulin is stored awaiting secretion. Both C-peptide and mature insulin are biologically active. Cell components and proteins in this image are not to scale.

In mammals, insulin is synthesized in the pancreas within the beta cells (β-cells) of the islets of Langerhans. One million to three million islets of Langerhans (pancreatic islets) form the endocrine part of the pancreas, which is primarily an exocrine gland. The endocrine portion only accounts for 2% of the total mass of the pancreas. Within the islets of Langerhans, beta cells constitute 60-80% of all the cells.

In beta cells, insulin is synthesized from the proinsulin precursor molecule by the action of proteolytic enzymes, known as prohormone convertases (PC1 and PC2), as well as the exoprotease carboxypeptidase E. These modifications of proinsulin remove the center portion of the molecule (ie, C-peptide), from the C- and N- terminal ends of proinsulin. The remaining polypeptides (51 amino acids in total), the B- and A- chains, are bound together by disulfide bonds/disulphide bonds. Confusingly, the primary sequence of proinsulin goes in the order "B-C-A", since B and A chains were identified on the basis of mass, and the C peptide was discovered after the others.

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14y ago

beta cells in islet of Langerhans (pancreas)

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13y ago

They're responsible for most of the insulin-stimulated uptake of plasma glucose.

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13y ago

Actually, insulin is produced by Beta cells which are essentially produced and located in Islet of Langerham ( in the endocrine pancreas)

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11y ago

Liver cells, as well as most other cells in the body.

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8y ago

They are liver cells. Some muscle cells can be affected

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8y ago

Mainly cells of liver. Also many muscle cells too,

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13y ago

Beta cells

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Q: Which cells secrete insulin
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What glands secrete hormones such as insulin?

The beta cells of the Isles of Langerhaans in the pancreas secrete insulin.


Which pancreatic cells secrete insulin?

A group called beta pancreatic cells produce insulin. Insulin is a molecule which carries glucose across the cell membrane. Alpha pancreatic cells produce glucagon which is involved in reducing glycogen stored in the liver into glucose.


Where is the islets of Langerhans located?

The Islets of Langerhans are pockets of endocrine cells in the pancreas. These cells produce glucagon and insulin. They are located near the small intestine.The Islets of Langerhans are pockets of endocrine cells in the pancreas. These cells produce glucagon and insulin.Found in the pancreas, which is located partially behind the stomach in the abdomen, it contains ACINAR cells which are involved in the digestive system. As for Islets of Langerhans, which are also found in the pancreas, there are beta cells which secrete GLUCAGON and alpha cells which secrete INSULIN, beta cells are more prevalent. Insulin and glocagon are secreted in response to blood glucose levels.Langerhans cells are dendritic cells in the epidermis, containing large granules called Birbeck granules. They are normally present in lymph nodes and other organs, including the stratum spinosum layer of the epidermis. They can be found elsewhere, but sould not be confused with the pancreatic cells of the islets of Langerhans.


The first organ to respond to rise in glucose blood level?

pancreas


How the action of the pancreatic hormones complement one another?

Beta cells secrete insulin, which lowers blood glucose and stimulates the production of glycogen. Alpha cells secrete glucagon, which raises blood glucose. The secretion of insulin is stimulated by a rise of blood glucose following meals. Glucogon is stimulated by a fall in blood glucose during periods of fasting.

Related questions

Beta cells which constitute 80 percent of the pancreases hormone producing cells secrete?

Beta cells secrete insulin, alpha cells secrete glucagon.


What do alpha cells secrete?

alpha cells just like beta and gamma cells secrete radiation. These were discovered by a french scientist in the 1800's


What glands secrete hormones such as insulin?

The beta cells of the Isles of Langerhaans in the pancreas secrete insulin.


What does the pancreas release?

The pancreas is endocrine (producing several important hormones, including insulin, glucagon, and somatostatin). The most important is insulin which controls the take-up of glucose by the body's cells.


Which pancreatic cells secrete insulin?

A group called beta pancreatic cells produce insulin. Insulin is a molecule which carries glucose across the cell membrane. Alpha pancreatic cells produce glucagon which is involved in reducing glycogen stored in the liver into glucose.


What cells in the pancreas that secrete glucagon are called?

Pancreatic beta cells produce insulin. They are the only cells in the body that do so.


Specialized islet cells that secrete hormones are found scattered throughout the?

Specialized islet cells that secrete hormones are found scattered throughout the Pancreas.


The islet cells of the pancreas secrete?

insulin and Glucagon - both are hormones which control glucose levels in the blood.


Where is the islets of Langerhans located?

The Islets of Langerhans are pockets of endocrine cells in the pancreas. These cells produce glucagon and insulin. They are located near the small intestine.The Islets of Langerhans are pockets of endocrine cells in the pancreas. These cells produce glucagon and insulin.Found in the pancreas, which is located partially behind the stomach in the abdomen, it contains ACINAR cells which are involved in the digestive system. As for Islets of Langerhans, which are also found in the pancreas, there are beta cells which secrete GLUCAGON and alpha cells which secrete INSULIN, beta cells are more prevalent. Insulin and glocagon are secreted in response to blood glucose levels.Langerhans cells are dendritic cells in the epidermis, containing large granules called Birbeck granules. They are normally present in lymph nodes and other organs, including the stratum spinosum layer of the epidermis. They can be found elsewhere, but sould not be confused with the pancreatic cells of the islets of Langerhans.


What is the name of the organ containing the glands that secrete insulin and glucagon?

Beta cells of the pancreas produce insulin.


Which organ system contains the pancreouse?

The islets of Langerhans are clusters of endocrine cells found in the pancreas. They secrete insulin and glucagon.


What part of the endocrine system secretes insulin?

good question! actually Pancreas is the gland that produces insulin. Inside the Pancreas are tiny cells called beta cells which form groups. The groups are called "Islets of Langerhans" which secrete insulin directly into the blood stream.