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Graves' disease is an autoimmune disease in which auto-antibodies attach to the TSH receptor sites throughout the body, including the thyroid gland.

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Q: Which disease is an autoimmune disease in which auto-antibodies attach to the TSH receptor sites on the surface of the thyroid gland?
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What is an autoimmune disease in which antibodies attach to the tsh receptor sites on the surface of the thyroid gland?

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Grave's disease is an autoimmune disease which causes hyperthyroidism.(particularly in the developed countries). normally TSH combines with the surface receptors of thyroid cells and causes the synthesis and secretion of thyroid hormones. in Grave's disease the thyroid stimulating autoantibodies (B-TSAB) produced by B lymphocytes activate the TSH receptors and increase the secretion of thyroid hormones(thyroxine and triiodothyronine). Grave's disease is due to elevated thyroid stimulating IgG also knoen as long acting thyroid stimulator (LATS) which activates TSH and, thereby, increases thyroid hormonal production.


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