calcium
The presence of an enzyme called acetylcholinesterasethat degrades acetylcholine is what prevents an accumulation of the neurotransmitter and sustained muscle contraction. Acetylcholinesterase is an enzyme that can be found within the neuromuscular junction. Thus, when a nerve impulse causes the release of acetylcholine at the neuromuscular junction, there is a critical time in which the neurotransmitter can bind to receptors on the muscle before it is degraded.
acetylcholine (ACh)
Acetylcholine is the excitatory neurotransmitter released by neurons innervating skeletal muscles. Acetylcholine release stimulates muscle contraction by acting at the nicotinic-acetylcholine receptor on the surface of the muscle cell.
If the action of acetylcholinesterase is inhibited, acetylcholine is not degraded and would accumulate in the synaptic cleft and act as a constant stimulus to the muscle fiber. The muscle cells will continue to contract resulting in a condition called spastic paralysis.
Acetylcholine
False
Alpha-Motor neurons release the neurotransmitter acetylcholine at a synapse called the neuromuscular junction. When the acetylcholine binds to acetylcholine receptors on the muscle fiber, an action potential is propagated along the muscle fiber in both directions.
The neurotransmitter acetylcholine is released into the synaptic cleft to bind with receptors on muscle cells. Upon binding, the muscle cells contract.
Acetylcholine
Acetylcholine
Acetylcholine
Smooth Muscle Cells