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The vitamin B12 is a very important nutrient; it lowers risk of stroke, Heart disease, cancer, Parkinson's, and Alzheimer's disease. The vitamin begins to absorb in the mouth, in contrast to most nutrients.

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13y ago
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14y ago

Intrinsic Factor is a glycoprotein produced by the parietal cells of the stomach. It is necessary for the absorption of Vitamin B12 (cyanocobalamin) later on in the terminal ileum. A deficiency in the intrinsic factor will lead to pernicious anemia.

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12y ago

Intrinsic Factor

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10y ago

Intrinsic factors.

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Q: Where does the absorption of vitamin B12 occur?
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A protein secreted by the stomach that is necessary for the absorption of vitamin B12?

"Intrisic factor" is necessary for B12 absorption


How long does it take for vitamin b12 to be absorbed?

It takes approximately 24 hours for the absorption of vitamin B12. For quicker absorption, you can get a B12 shot.


Which vitamin need instritic factor for stomach for absortion?

B12 is the vitamin that requires intrinsic factor for absorption. B12 is also known as cobalamin.


What carrier protein is responsible for absorption of vitamin B12?

Intrinsic factor


When does vitamin B12 anemia occur?

Vitamin B12 deficiency anemia is another type of megaloblastic anemia that develops when the body doesn't absorb enough of this nutrient.


The absorption of which vitamin would be impaired by the removal of the stomach?

Vitamin B12 is released from proteins by concentrated levels of HCL acid in the stomach. Therefore, without the stomach there would be no HCL acid to release the B12


Aids in absorption of vitamin b12?

It is called intrinsic factor, which enables the absorption of B12. Intrinsic factor is found in the parietal cells (mucosa cells) of the stomach lining.


Is B12 a vitamin or a mineral?

B12 is a vitamin


Is b12 bad for you?

If you are referring to vitamin b12, vitamin b12 is healthy for you.


Why oral administration of vitamin B12 not effective as a treatment of pernicious anemia?

Pernicious anemia is due to a deficiency of a vitamin called intrinsic factor, which is normally produced by cells of the stomach. Intrinsic factor is required for the absorption of vitamin B12, so if intrinsic factor levels are insufficient, vitamin B12 will not be absorbed well. So administration of vitamin B12 will only help treat vitamin B12-deficiency anemia if vitamin B12 can be absorbed, and this can only happen if there are adequate levels of intrinsic factor to begin with. Patients with pernicious anemia do not have adequate intrinsic factor levels, so they will not be helped by vitamin B12 treatment since they can't absorb it well enough.


Where does the body store vitamin d?

Vitamin B12 is absorbed in the terminal ileum (the last part of the small intestine). The process of absorption occurs by dietary B12 becoming bound to R-protein in the saliva, the B12 is then cleaved from R-protein by the acidic conditions in the stomach. Gastric parietal cells secrete a substance called Intrinsic Factor, which binds the B12. In the terminal ileum there are receptors for intrinsic factor and both are absorbed. Problems with this absorption can occur if the body makes auto-antibodies to intrinsic factor, this means there is problems with B12 absorption and a condition called pernicious anaemia can result. The answer you wanted is the first line, but I hope the extra information is either helpful or of interest. Pete (medical student in the UK)


What is the recommended treatment for pernicious anemia?

Pernicious anemia can be treated with injections of vitamin B12, and possibly with B12 vitamin pills. Pernicious anemia is a vitamin B12 deficiency disease, B12 is required to make healthy red blood cells and can normally be obtained from animal based foods, including, meats, fish, dairy products and eggs (but not plant foods), however, when people choose not to eat animal products, vegans for instance, they may suffer a B12 deficiency. Also, inadequate absorption can occur when there is an insufficient amount of a specific protein referred to as "intrinsic factor" in the body that is normally released by stomach cells.