They are needed for contraction and also for relaxation:
- For contraction: actin has active sites for binding to myosin, and myosin heads have ATPase activity (ATP hydrolization provokes a conformational change in the myosin head that pushes the actin filament and that is called the "power stroke), and at the end the sarcomere (sorry, Google it) shortens. This repeats until calcium levels get lower again (because calcium allows actin to bind myosin, because there are other proteins - troponin, tropomyosin - that block this binding when calcium is not present). This is the cross-bridges cycle.
- For relaxation: we have said that calcium ions are necessary for contraction, but we don't want our muscles to contract forever. That's why we need a mechanism to reduce intracellular calcium concentration. That mechanism is a calcium pump (called SERCA) that puts calcium ions again inside the "sarcoplasmic reticulum", which is a kind of storage compartment for calcium in skeletal muscle. This sarcoplasmic reticulum is very developed in skeletal muscle (in contrast with smooth muscle). SERCA pumping is also ATP dependent (active transport). As a curiosity, inside of the sarcoplasmic reticulum, calcium ions (Ca2+) bind to another protein called calcequesterin.
They are needed also for processes intrinsic of excitable cells (aka neurons and muscle cells), such as the sodium-potassium pump (active transport)
obtained from a coupled reaction of creatine phospate w/ATP and from aerobic and anaerobic metabolism of glucose Chapter 9 get with it 20 hours of study time man
If you think about it, skeletal muscle are muscles that connect bones. So wherever you have bone, it is covered with skeletal muscle. Muscles do not connect bones. Muscles are the source for movement and protection for bones.
Skeletal
Resting skeletal muscles burn glucose for energy. Although fat can also be used as an energy source, if glucose is present, muscles will use glucose first.
The preferred source of energy for the heart muscle is fatty acids. Fatty acids are "good fats" that are main sources of energy for cells.
the sun
The sun
The sun.
the sun
The ultimate source of energy for life processes comes from the sun. This energy enters the earth's food chains through photosynthesis.
The ultimate source of energy for life processes comes from the sun. This energy enters the earth's food chains through photosynthesis.
The ultimate source of energy for life processes comes from the sun. This energy enters the earth's food chains through photosynthesis.