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The most affected joints would be the larger joints. Examples: the shoulder, the knees, elbows, and sometimes the hips.
In my case, my hips, knees and wrists are the main ones, yet every joint is affected just not as much as those
Joint inflammation in the knees and other large joints.

Lyme Arthritis usually affects the knees. In a minority of patients arthritis can occur in other joints, including the ankles, elbows, wrist, hips, and shoulders. Pain is often mild or moderate, usually with swelling at the involved joint. Baker's cysts may form and rupture. In some cases joint erosion occurs.

http://www.nlm.nih.gov/medlineplus/ency/article/000625.htm

http://en.wikipedia.org/wiki/Lyme_disease

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Q: Which type of joint would be most affected by Lyme disease?
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