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Who gives oxygen atom in ester synthesis?

Updated: 11/1/2022
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Somnath25903

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12y ago

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It depends on which reaction is used to create the ester. When catalyzing a carboxylic acid with a strong base such as NaOH, then using an alkyl halide, the oxygen is from the acid.

R-COOacidH + NaOH -> R-COO-acid + R'X ->R-COOacidR'

When using a carboxylic acid with an alcohol or an acid chloride with an alcohol, the oxygen originates from the alcohol.

R-COOacidH + R'OalcoholH + HCl -> R-COOalcoholR'

R-COOacidCl + R'OalcoholH + Pyridine -> R-COOalcoholR'

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