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Which substance is both filtered and secreted by the nephron and is therefore used to measure the renal plasma flow and estimate the total renal blood flow?
para-aminohippuric acid (PAH)
What is meant by hematologic clearance?
Clearance refers to the renal excretion ability. Hematologic clearance refers to rate at which waste substances have been cleared from the blood.
What percent renal plasma clearance via tubular secretion?
80%
Why does renal failure lead to hyperprolactinemia?
Renal failure and cirrhosis cause delayed clearance of prolactin as it is metabolized by both the kidney and liver the serum prolactin concentration is high in patients who have chronic renal failure and returns to normal after renal transplantation . The major mechanism is a three-fold increase in prolactin secretion, and there is a one-third decrease in metabolic clearance rate
What does a renal clearance test so?
An adaptation of the epithelial cells of the proximal civilities tubule for reabsorption is
Define and explain Total Body Clearance?
Total body clearance can be defined as the volume of blood/biological fluids completely cleared of drug per unit time. It is equal to the sum of Renal clearance (CLr) and hepatic clearance (CLh).
Which major crime has the highest clearance rate?
murder
When was Oom-Pah-Pah created?
Oom-Pah-Pah was created in 1960.
What are the release dates for Oom Pah Pah - 1930?
Oom Pah Pah - 1930 was released on: USA: 11 May 1930
Who sings oom-pah-pah in Oliver?
hi there in the musical and film of "Oliver" it is Nancy and her friend bett that sing oom pah pah
What is the normal creatinine clearance level during pregnancy?
Normal creatinine clearance in most people is over 60 mL/min, however, in pregnancy it is increased by as much as 50% because of increased GFR and renal plasma flow.
How are Log D values related to drug clearance and toxicity?
Drugs with a log D value above 0 at pH=7.4 are usually metabolised by the liver's P450 enzymes. This is because they tend to decrease renal clearance so they have to be cleared metabolically.
