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Why are drugs in solid form unlikely to be absorbed in the stomach to any significant extent?
Wiki User
∙ 7y ago
Only the lipid soluble non-ionized form of a drug can diffuse across the membrane. The pH is low in the stomach. For the acidic drugs, they are non-ionized at low pH yet they are poorly soluble. For the basic drugs, they are soluble yet ionized.
Wiki User
∙ 7y ago
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