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Migraines begin with a spreading cortical depression, which is a fancy way of saying that there are changes in neurological activity across the entirety of the brain. The entire brain becomes overstimulated - causing changes in nerve firing, causing changes in serotonin (which affects how we perceive pain), sometimes causing dilation of blood vessels. In short - your nerve endings aren't responding appropriately to anything. Stress has been removed from the IHS (International Headache Society's) list of triggers, although those under stress often do things that trigger their Migraine attacks.

It has been postulated that those who have migraines may have this heightened sensitivity all the time - just not to the degree they have it when they are having a migraine. Although it is considered anecdotal evidence at this point, many migraineurs report having a stronger sense of olfactory, auditory, and visual sensitivity than those around them. This original heightened sensitivity, for many can trigger migraines in the first place.

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Q: Why are your senses heightened when you have a migraine?
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