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Q: Why bilirubin is increased in Haemophilia?
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What is TBIL on a blood test?

Bilirubin is a breakdown product of heme (a part of haemoglobin in red blood cells). The liver is responsible for clearing the blood of bilirubin. It does this by the following mechanism: bilirubin is taken up into hepatocytes, conjugated (modified to make it water-soluble), and secreted into the bile, which is excreted into the intestine. Increased total bilirubin causes jaundice, and can signal a number of problems: 1. Prehepatic: Increased bilirubin production. This can be due to a number of causes, including hemolytic anemias and internal hemorrhage. 2. Hepatic: Problems with the liver, which are reflected as deficiencies in bilirubin metabolism (e.g. reduced hepatocyte uptake, impaired conjugation of bilirubin, and reduced hepatocyte secretion of bilirubin). Some examples would be cirrhosis and viral hepatitis. 3. Posthepatic: Obstruction of the bile ducts, reflected as deficiencies in bilirubin excretion. (Obstruction can be located either within the liver or in the bile duct.)


Is there a cure for haemophilia?

There is no "cure" for haemophilia, only treatment with the appropriate clotting factors.


What is bilirubin?

Bilirubin is a pigment in bile created during the breakdown of haemoglobin, which is then excreted from the body in bile. It is bilirubin which gives people the characteristic yellow colour in jaundice (whether that be caused by liver failure, obstruction or an increased breakdown of haemoglobin).the liver


What causes yellow face?

increase levels of bilirubin in blood due to increased production as in rapid destruction of red blood cells. more commonly it is due to decreased elimination of bilirubin because of liver disease.


What are the pigments released by the liver in bile called?

From the glossary of medical terms the answer is: BILIRUBIN


Jaundice is caused by the rapid breakdown of?

Jaundice is caused by the rapid breakdown of red blood cells which leads to increased levels of bilirubin.


High levels of billirubin in the blood stream can result in?

jaundice the normal serum bilirubin level is 0.5 to 1.5mg%. jaundice occurs when the bilirubin level exceeds 2mg%. the increased blood level of bilirubin is called hyperbilirubinemia. excess bilirubin from blood diffuses into the tissues, skin and mucous membrane, colouring them yellow. this condition caused by overflow of bilirubin is called jaundice.


How can you tell if bilirubin has affected my child?

Bilirubin is the pigment that makes feces brown."Failure of the liver cells to excrete bile, or obstruction of the bile ducts, can cause an increased amount of bilirubin in the body fluids and thus lead to obstructive or regurgitation jaundice.Another type of jaundice results from excessive destruction of erythrocytes (hemolytic or retention jaundice). The more rapid the destruction of red blood cells and the degradation of hemoglobin, the greater the amount of bilirubin in the body fluids.Most bilirubin is excreted in the feces. A small amount is excreted in the urine as urobilinogen."answers.com


What is the color of bilirubin?

The color of Bilirubin is orange Bilirubin is an orange color pigment in the bile


Are eyes effected by primary biliary cirrhosis?

Possibly - One of the symptoms is Jaundice (yellowing of the eyes and skin), due to increased bilirubin in the blood.


How many people in the population have haemophilia in the world?

Haemophilia (also spelled hemophilia) is genetic disorder. It is more licely for a male to get it than female. About one of 5,000-10,000 male babies are born with Haemophilia A. About one of 20,000-34,000 male babies are born with Haemophilia B.


How do people suffer with haemophilia?

Haemophilia is a genetic disorder. Usually males are the victims and females are carriers of this disease. There is no prominent cause of this disease but now-a-days it is seen that the families which do not have any history of haemophilia may also have a haemophiliac child. The reason for this is that sometimes there is mutation at genetic level which may lead to deficiency of clotting factor(VIII OR IX) in the blood of the child resulting in haemophilia. One may also suffer from haemophilia at a very later stage of his life but that is very rare. This is the case of Acquired Haemophilia.