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Because a protein's function is dependent on is shape, and a mutation may change the composition (the sequence of amino acids) of a protein, which may in turn cause the shape of the molecule to change.
Wiki User
∙ 8y ago
Wiki User
∙ 13y agoA mutation can either remove, add, or substitute a nitrogen base (guanine, uracil, adenine, and cytosine). When a cell starts protein synthesis, the DNA inside the nucleus will create a strand of RNA to take a copy of the DNA to a ribosome to create a protein. When the transfer RNA brings the opposite nitrogen base (if the RNA has GGC, the transfer RNA will bring CCG), it will bring the incorrect nitrogen base to make an amino acid, due to the mutation that either removed, added, or substituted the correct base. For example, if an amino acid was suppose to be a CAU amino acid, but the C was substituted for a G, the amino acid would be GAU instead of CAU. And, since amino acids make up proteins, the cell would not make the correct protein. In short, the mutation affects the nitrogen bases in the DNA which affects the RNA which affects the amino acid which affects the protein.
Wiki User
∙ 14y agoThe protein can become inactive. This is called a null mutation.
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Which type of mutation causes the most change to the protein produced?
A silent mutation
When a nitrogenous base is inserted or delete how does that affect the amino acid sequence?
The amino acid sequence is shifted, and this kind of mutation is called a frame shift mutation. All of the amino acid sequence after the mutation will be changed, which will cause a change in shape of the protein, which will then probably result in a nonfunctional protein, since the shape of a protein determines its function.
What happens when there is a mutation in a 5' UTR of mRNA?
If there is a mutation in the 5' UTR no change in the protein function and abundance will happen.
Why does mrna mutation affect the amino acid sequence?
The codon UGU codes for the amino acid Cysteine. The codon UGG codes for the amino acid Tryptophan. Therefore the mutation will cause the amino acid Cysteine to be replaced with Tryptophan. These amino acids are quite different, and the final shape of the protein could be changed as a result. This could affect the function of the protein.
Explain how a mutation could have no effect on the organism?
It can have absolutely no affect, a bad affect, or even a good affect.*Deletion and Addition are frameshift: most harmful.
Which type of mutation causes the most change to the protein produced?
A silent mutation
How is it possible for a point mutation to have no effect on the function of gene?
If the point mutation does not change the protein to be translated in the 3-letter sequence, then it will have no effect on the gene's function.
How a mutation during replication can affect a protein that is synthesized?
A mutation during replication can affect a protein that is synthesized in a variety of ways. Mutations can mess up the protein sequences and cause different proteins to be synthesized.
When a nitrogenous base is inserted or delete how does that affect the amino acid sequence?
The amino acid sequence is shifted, and this kind of mutation is called a frame shift mutation. All of the amino acid sequence after the mutation will be changed, which will cause a change in shape of the protein, which will then probably result in a nonfunctional protein, since the shape of a protein determines its function.
Why does an insertion mutation usually cause more defects in protein synthesis than a point mutation?
Insertion mutations can affect many amino acids in the protein.An insertion mutation usually causes more defects during protein synthesis than point mutation because an insertion mutation will affect many amino acids in the protein.
Why does an insertion mutation usually cause defects during protein synthesis than a point mutation?
Insertion mutations can affect many amino acids in the protein.An insertion mutation usually causes more defects during protein synthesis than point mutation because an insertion mutation will affect many amino acids in the protein.
Why does an insert mutation usually cause more defects during protein synthesis than a point mutation?
Insertion mutations can affect many amino acids in the protein.An insertion mutation usually causes more defects during protein synthesis than point mutation because an insertion mutation will affect many amino acids in the protein.
What happens when there is a mutation in a 5' UTR of mRNA?
If there is a mutation in the 5' UTR no change in the protein function and abundance will happen.
What One example of a mutation that would not affect an organisms phenotype?
A Missense Mutation.It is a point mutation where the mutations alters the base sequence without changing the resulting function of the subsequent protein. This is usually when the mutation does not change the amino acid which the codon codes for.
How can a single mutation in a protein such as hemoglobin affect several body system?
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What cell mutation does not impact the phenotype of the organism because the protein remains unchanged?
It is possible for a point mutation to not change the sequence of amino acids in a protein. This will result in the protein being unchanged and will not affect the phenotype.
Why does mrna mutation affect the amino acid sequence?
The codon UGU codes for the amino acid Cysteine. The codon UGG codes for the amino acid Tryptophan. Therefore the mutation will cause the amino acid Cysteine to be replaced with Tryptophan. These amino acids are quite different, and the final shape of the protein could be changed as a result. This could affect the function of the protein.
