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Can a frameshift mutation be a silnt mutation?
A frameshift mutation completely changes the genetic code from the point of the mutation, so the protein made as a result of the mutation would have the incorrect structure and would not function as it should.
When a nitrogenous base is inserted or delete how does that affect the amino acid sequence?
The amino acid sequence is shifted, and this kind of mutation is called a frame shift mutation. All of the amino acid sequence after the mutation will be changed, which will cause a change in shape of the protein, which will then probably result in a nonfunctional protein, since the shape of a protein determines its function.
As a result of the incorrect sequence of amino acids will be translated into a protein-resulting in a mutation?
Missence mutation
What is a A genetic mutation that does not result in a change in the amino acid sequence of the resulting protein is called?
a silent mutation.
Which type of mutation will probably have a larger effect A point mutation or a frameshift?
Both types of mutation have the potential to cause a large effect.In general, a frameshift mutation is more likely to cause a large effect. This is because it shifts the 'reading frame' - so that all of the subsequent codons (groupings of 3 bases that are read to determine which amino acid will be added) will be changed.A point mutation is when a single base is replaced. This can either result in the same amino acid being added to the protein being synthesised (a silent mutation), a different amino acid being added (a missense mutation) or in a STOP codon (a nonsense mutation).If a point mutation causes a premature STOP codon - this is quite likely to have a large effect on the protein.
Can a frameshift mutation be a silnt mutation?
A frameshift mutation completely changes the genetic code from the point of the mutation, so the protein made as a result of the mutation would have the incorrect structure and would not function as it should.
How would a protein be changed if a mutation caused a base to be added?
A mutation in which an extra nitrogen base is added is called a frameshift mutation. The rest of the sequence after the mutation will code for different amino acids, which will result in the alteration of the protein. Frameshift mutations cause severe genetic disorders.
What can occur as a result of a change in the sequence of nucleotides in a strand of DNA?
The addition or deletion of a nucleotide can lead to a Frameshift mutation. The Frameshift mutation causes a "shift" in the reading frame of the codons in the mRNA. This may lead to the change in the amino acid sequence at protein translation.
When a nitrogenous base is inserted or delete how does that affect the amino acid sequence?
The amino acid sequence is shifted, and this kind of mutation is called a frame shift mutation. All of the amino acid sequence after the mutation will be changed, which will cause a change in shape of the protein, which will then probably result in a nonfunctional protein, since the shape of a protein determines its function.
How do mutations affect translations?
A frameshift mutation may cause a change in the codon sequence, specifically the 3-base sequence which is responsible for coding a specific amino acid. A different protein, a non-functional one, or no protein at all may be the result of this change.
When when a mutation results in no significant change in the production of a of a functional protein?
When a mutation does not change the result of a normal production of a protein is called harmless. This is because it does no harm to the individual.
As a result of the incorrect sequence of amino acids will be translated into a protein-resulting in a mutation?
Missence mutation
Which do you suppose would be more harmful A mutation that changed the nucleotide sequence of an mRNA molecule or a mutation that changed the nucleotide sequence of a DNA molecule?
A mutation in a DNA nucleotide sequence would be more harmful than a mutation in a mRNA nucleotide sequence because it could cause the synthesis of multiple nonfunctional proteins in comparison to a mutation in a mRNA nucleotide sequence that would be less harmful because it would result in a few nonfunctional proteins.
What is a A genetic mutation that does not result in a change in the amino acid sequence of the resulting protein is called?
a silent mutation.
Which type of mutation will probably have a larger effect A point mutation or a frameshift?
Both types of mutation have the potential to cause a large effect.In general, a frameshift mutation is more likely to cause a large effect. This is because it shifts the 'reading frame' - so that all of the subsequent codons (groupings of 3 bases that are read to determine which amino acid will be added) will be changed.A point mutation is when a single base is replaced. This can either result in the same amino acid being added to the protein being synthesised (a silent mutation), a different amino acid being added (a missense mutation) or in a STOP codon (a nonsense mutation).If a point mutation causes a premature STOP codon - this is quite likely to have a large effect on the protein.
What would Translation of the DNA sequence AAGCTGGGA would result in?
This would result in a frameshift mutation. This would cause the protein, after translation, to be truncated and would most likely be non-functional. This is due to a change in the amino acid sequence and would stop the protein from forming the correct secondary and tertiary structures due to a change in the electrostatic/ hydrophobic/ h-bonding etc. parameters of the protein
Caused by the insertion or deletion of nucleotides in DNA?
The deletion or insertion of one nucleotide into the DNA sequence will result in a frameshift mutation which changes the reading frame that the tRNA follows when assembling amino acids from the DNA sequence. Each amino acid is coded for by a codon of three specific nucleotides. Shifting this frame can result in a different amino acid being added to the growing polypeptide chain. Also, a stop codon can be read and thus prematurely end the polypeptide chain. This creates incorrect and/or incomplete proteins. This could lead to serious problems if essential proteins are being saccrificed due to the mutation.
