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To the best of my knowledge, blood becomes less acidic because more CO2 is removed from the alveoli through breathing.

To understand this, you need to know how gas exchange mechanism in your body works. First off, when you breath, gas exchange occurs in lung's alveoli (little sacs in your lungs). The O2 that is breathed in will replace the CO2 in the blood cells. The CO2 is then pushed to the alveoli and gets blown off as you exhale.

Now, how is CO2 related to blood acidity?

- In the blood, CO2 and H2O react with each other to form H2CO3 (carbonic acid). See how it works now? This carbonic acid makes your blood more acidic when presence.

So what happens if you breath harder and rapider?

- More CO2 gets blown off.

When more CO2 is removed from the circulation, the lower the H2CO3 is produced by the reaction between CO2 and H2O, the more pH increases, and the blood is less acidic.

And as the CO2 level becomes too low, and the blood is too alkaline; the action reverses.

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Q: Why is blood less acidic when hyperventilating?
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