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This is called denaturing.
Denatured
it alters the pH of the enzyme denaturing it leaving it unable to carry out it's role effectively or at all
pH Temperature Substrate Concentration non-ideal conditions will ultimately lead to the denaturing of the enzyme
yes it is. however fabrazyme (enzyme replacement therapy) can stop most major damage and prolong life.
If you denature an enzyme, you do not kill it because it was never alive, but you shut it down. It cannot work any longer and therefore it cannot speed up the reaction. The overall reaction will be slower because there are less enzymes.
Just like always, deviating from the desired normal functioning for the enzyme, whether it be in temperature or pH, would result in the enzyme denaturing and therefore being unable to for enzyme substrate complexes, therefore reducing the overall reaction rate.
Enzymes are proteins that help speed up the the rate of chemical reactions in the human body. Enzymes possess a specific shape and this shape fits into the substrate. When an enzyme becomes denatured, it loses its shape and thus it cannot function effectively. Enzymes may become denatured due to high temperatures or changes in the pH.
It is not life threatening if it is minor.
He had a life-threatening illness.
All enxymes work at an optimum pH. Changes in pH levels could change the rate at which the enzymes work by denaturing them.
Yes, having a higher than normal kidney enzyme reading can be critical and life threatening. Your doctor will run other tests and might start treatments to get the levels under control.