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"X-linked" disorders are more commonly observed in males do to the chromosomal make up of boys and girls. As you are probably already aware, females have two X chromosomes and no Y chromosomes. Males on the other hand have one Y chromosome and only one X chromosome.
Since this is the case, when a male receives an X chromosome with a mutation on it, they have to use that X chromosome as a "blueprint" even if the information on it is wrong. When a female has a mutation on one of her X chromosomes, she typically has another non-mutated X chromosome from which she can get the correct information.
Wiki User
∙ 12y ago
Wiki User
∙ 13y agoHemophilia is passed down from mother to son. It is extremely
rare for a woman to have hemophilia. It is necessary, though, for
a woman to be a carrier of the disorder for her son to acquire this
disorder. Females have two X chromosomes whereas males only
have one. When a boy is born, he takes one X chromosome from
his mother and one Y chromosome from his father. Therefore, he
can only get hemophilia through his mother.
Example One:
Mother(Carrier)+Father(Non-Affected)=50% chance of their son
acquiring the disorder and 50% chance of their daughter being a
carrier.
Example Two:
Mother(Non-Affected)+Father(Hemophiliac)=All sons will be
non-affected and all daughters will be carriers.
Since a woman has two X chromosomes, even if one is infected with hemophilia, the other most likely will not be and
will still be able to produce the proteins needed for the blood to clot. To have hemophilia, the woman would have
had to acquire an infected X chromosome from her mother and then an infected X chromosome from her father.
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The hereditary disease in which clotting does not occur is known as?
hemophilia
Are some boys carriers for hemophilia?
A male with hemophilia does in fact carry the genes and can pass them on to his daughters, so yes, some boys (if they have hemophilia) are carriers.
What are the statistics of hemophilia?
1 in 5,000 male birth
Is hemophilia mostly seen in males?
Yes. Mostly males. It is exceedingly rare for a woman to acquire hemophilia(unless she is a carrier of it). Women have a diminutive chance of having this genetic disorder.
What chromosomes does hemophilia occur on?
Hemophilia is a X linked recessive disorder. Usually the mother is an unaffected carrier and her son unfortunately receives the X chromosome in which hemophilia is linked to.
Why Hemophilia more common in male than in female?
The genes associated with Hemophilia A and B are located on the X chromosome, which is one of the 2 sex chromosomes. For males, who have only 1 X chromosome, 1 altered copy of the gene in each cell is sufficient to cause hemophilia. In females, who have 2 X chromosomes, a mutation would have to occur in both copies of the gene to cause hemophilia. Since it is unlikely that females will have 2 altered copies of this gene it is therefor very rare for females to have hemophilia.
What gene does hemophilia affect?
The gene that causes hemophilia is located on the X chromosome. A woman who gives birth to a child with hemophilia often has other male relatives who have hemophilia. Sometimes, a baby will be born with hemophilia when there is no known family history. This means the gene can be"hidden"( or passed down through several generations of female carriers without affecting any male members of the family) or the change in the X chromosome is new (a spontaneous mutation).
Why is hemophilia considered to be a sex link trait?
Because the gene that causes hemophilia is located on the X chromosome, so it will occur in males more frequently than in females.
When and where do tornadoes mostly occur?
they most likely occur in Florida or the mostly occur in Texas
How can a lady have hemophilia will it effect menstrual period?
Normally a woman is only a carrier of hemophilia, but if her mother is a carrier and her father has hemophilia the female does have a chance to get it. It is very rare for this to happen but It has been recorded.
What is the percentage of the population suffering from hemophilia?
Hemophilia A occurs once in every 10,000 people in the U.S., or one in every 5,000 males. Hemophilia B occurs once in every 50,000 people. 400 babies are affected every year in the United States, a large majority of them male.
Where and when do earthquakes mostly occur?
They mostly occur when the tectonic plates in the earths systems rub against each other and they mostly occur in California.
