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By using the anatomical position, a reference point is created, thus eliminating confusion. Since directional language, such as the words, "up," "down," "left," "right," "above," and "below" are subjective and can vary depending on many factors. By using one uniform position when examining a person's body, these terms are less likely to be misunderstood or poorly communicated. How the person's body is positioned can greatly change the layout of the person's anatomy and thus change the terms used to describe the person's anatomy.

For example, when the palms are facing upwards or forwards, as they should be in the anatomical position, they are supine. If the palms are facing downwards or backwards, which they should not be in the anatomical position, they are prone. When the palms are supine, the two bones in the forearm, the radius and ulna, are parallel to one another. When the palms are prone, the radius and ulna cross over one another.

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