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Why is more 02 unloaded from hemoglobin in an actively metabolizing tissue than in a resting tissue?
Tarynhiccups17
A reduction in blood flow to NONcritical body areas explains why Oxgen is unloaded from hemoglobin in the active metabolizing tissue than in a resting tissue.
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∙ 12y ago
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Why does oxygen leave the hemoglobin when it passes through the resting tissues?
The oxygen is carried by Hemoglobin to the Tissues! What happens is, that there's something called the Allosteric Inhibition! Which means, when the Hemoglobin reaches the tissue, there will be lots of Co2 released in the tissue, during release of energy, the partial pressure of co2 inside the tissue will be high, so that with pressure gradient, it will travel outside the tissue to the artery and then into the hemoglobin where it binds to different sites and when that happens, it allosterically inhibits the Hemoglobin molecule to let go of Oxygen, and the oxygen is bounded as per cooperativity which means when one oxygen is bounded it will be easier for others to get bound to it, and in the same way when co2 attaches itself to the Hemoglobin, the oxygen start to disassociate as the Hemoglobin changes its shape and once one oxygen molecule leaves the hemoglobin it would be harder for the molecule to hold on to the rest of the 3 molecules! So in such way the oxygen leaves the hemoglobin!
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When was A Troubled Resting Place created?
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