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Why is sodium bicarbonate used to help increase the poor absorption of a drug?
Wiki User
∙ 15y ago
because orally ingested drugs have to be soluble and is a major synthetic goal of medchem scientists
the way you make a drug more soluble is to make it an ion (thats why you see many drugs are XXXXX HCl) and bicarbonate can be used to abstract an acidic hydrogen from the drug molecule and make it ionic (so more soluble)
Wiki User
∙ 15y ago
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What are the polymers used in prolonged drug delivery?
Sodium, calcium, bicarbonate
Does laxative increase or decrease drug absorption?
decrease
What drug blocks the effects of aldosterone?
Caffeine binds to aldosterone sites and thus causes an increase of aldosterone in the blood. This increase causes sodium re-absorption and potassium excretion. Sodium excites nerves as potassium relaxes them. This is why one looses their nerve with too much caffeine.
What is the effect of decreased albumin concentration on drug's absorption?
The effect of decreased albumin concentration on drug absorption is that it may cause first-pass metabolism. This may increase gastric pH levels as well.Ê
Where to buy sodium carbonate solution for baking?
From a chemical supply house.
What is effect of pH on absorption of a drug?
the more ionized the drug is the less absorption
What is sodium bicarbonate used for in a medical emergency?
Sodium bicarbonate is used as an IV solution in some emergencies such as cardiac arrest, circulatory insufficiency due to shock or severe dehydration, and in severe primary lactic acidosis or severe diabetic acidosis. It may also be used in some cases of drug overdoses, including barbiturates (where dissociation of the barbiturate-protein complex is desired), in cases of poisoning by salicylates (like aspirin) or methyl alcohol poisoning. It also may be used in cases of severe diarrhea which is often accompanied by a significant loss of bicarbonate although this might not really qualify as an emergency. In some cases it also works to administer the sodium bicarbonate orally to help with treatment of poisoning - for example - to inhibit absorption of aspirin in cases of aspirin overdose by raising the pH of the stomach and gut contents to a more neutral level (aspirin needs an acidic environment for absorption).
What is veterinary drug absorption?
Veterinary drug absorption is the uptake of a drug after administration so that it can cause some sort of alteration in the body.
Importance of pka value in drug absorption?
if Pka value is more for acidic drug,best side for absorption will be throughout the G.i.Tract.
Why does crack cocaine have greater drug toxicity potential than cocaine?
Crack is a mixture of cocaine and sodium bicarbonate which causes a strong reaction of chemicals and enhances their effect on the central nervous system.
What factor increase rate of absorption of drug?
If you want just one factor, body weight could be it. Heart rate can also affect absorption rates. Muscle to fat ration can affect absorption. Whether you have recently eaten or drank water can be a factor. Alcohol can also affect absorption rates. Pick one I guess.
Will b12 enhance Adderall?
Not sure about b12, but anything that is considered a "base" such as milk, tums, or other antiacids will increase absorption of adderall. Anything acidic, such as citrus, fruit juices, ect. will decrease absorption and weaken the overall effect of the drug.
