Why would only drivers side power windows and locks stop working in a 2003 Chevy trailblazer?

Most likely a broken wire in the hinge area of the door.

Here's how to remove the trim panel

http://www.ricksfreeautorepairadvice.com/uncategorized/remove-a-door-trim-panel-from-any-vehicle%E2%80%94-without-a-diagram

Here's how to test the window motor

http://www.ricksfreeautorepairadvice.com/repair-topics/window-power-repair/replace-a-power-window-regulator