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Q: Would a 3-nucleotide insertion result in a frameshift?
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What would produce a frameshift mutation?

An insertion/deletion event.


Can a frameshift mutation be a silnt mutation?

A frameshift mutation completely changes the genetic code from the point of the mutation, so the protein made as a result of the mutation would have the incorrect structure and would not function as it should.


Would protein be the same if a new base was inserted into the strand of DNA?

No. At the point of insertion the sequence would be completely changed. This is called a frameshift mutation.


What mutations would be considered frameshift mutations?

In mature mRNA, there is a start codon (AUG) that instructs ribosome to begin translation. Thereafter, every 3 bases are read as a "code word" calling for a particular amino acid to enlogate the polypeptide chain or to STOP and release the polypeptide. If 1 or 2 nucleotides are deleted or inserted into this sequence, it causes the reading frame to shift. This usually results in misreading of the sequence here is an example: AUG - AGC - ACC - TAA - GGG - etc. (if we delete the first C we get....) AUG - AGA - CCT - AAG - GG ( this is obviously not going to code for the same amino acid sequence)


Is pku a point shirt or a frameshift mutation?

PKU (phenylketonuria) is a point mutation, specifically an autosomal recessive genetic disorder caused by a mutation in the PAH gene. This mutation leads to impaired metabolism of the amino acid phenylalanine. It is not a frameshift mutation, which would involve an insertion or deletion of nucleotides, shifting the reading frame of the gene.


How would a protein be changed if a mutation caused a base to be added?

A mutation in which an extra nitrogen base is added is called a frameshift mutation. The rest of the sequence after the mutation will code for different amino acids, which will result in the alteration of the protein. Frameshift mutations cause severe genetic disorders.


Which is more harmful frameshift mutation or point mutation?

point mutations include substitutions insertions and deletions of single nucleotides in DNA. insertions and deletions have a greater effect on proteins than do substitutions because insertions and deletions affect every amino acid that is specified by the nucleotides that follow the point mutation. in contrast a substitution affects a single amino acid. a change in more than one amino acid is more than likely to alter the ability of the protein to function normally than is a change in a single amino acid


What would Translation of the DNA sequence AAGCTGGGA would result in?

This would result in a frameshift mutation. This would cause the protein, after translation, to be truncated and would most likely be non-functional. This is due to a change in the amino acid sequence and would stop the protein from forming the correct secondary and tertiary structures due to a change in the electrostatic/ hydrophobic/ h-bonding etc. parameters of the protein


How do you boof?

Boofing is the art of anal insertion. A legitimate boof is one that many Boofers would refer to as "knuckle deep". not going knuke deep would result in an incorrect boof. Boofing is known to get you as high as you possibly can.


What would increase cystitis?

insertion of a urinary catheter


How many polypeptides would this DNA template code for?

There would be 5 polypeptide bonds if you are working on the "Whats the point?"-- Point frameshift, inversion, and Deletion Mutations worksheet.


Would you administer pain medication before chest tube insertion?

no