all mutations in terms of DNA happen in a gene. here it has to be noted that a gene is made up of two strands of nucleotides which are made up of amino acids. when mutations occur the sequence of nucleotides may change. sometimes a nucleotide may become missing hence the sequence of the strands change. mutations can be harmful but also very beneficial.
Changes in a DNA sequence of a single gene is called a point mutation. These mutations can be harmful or not to the organism.
Random mutations of DNA happen and these get inserted into the gene pool as the species breed.
Mutations are permanent.
A gene mutation is a permanent change in the DNA sequence that makes up a gene. Mutations range in size from a single DNA building block (DNA base) to a large segment of a chromosome. A chromosomal mutation is a mutation involving a long segment of DNA, it is a any change in the structure or arrangement of the chromosomes. These mutations can involve deletions, insertions, or inversions of sections of DNA. In some cases, deleted sections may attach to other chromosomes, disrupting both the chromosomes that loses the DNA and the one that gains it.It is also referred to as a chromosomal rearrangement The differences between Gene mutation and Chromosome mutation are ; 1- Chromosome mutations involve changes in the structure of a chromosome OR the loss or gain of a chromosome while Gene mutations involve a change in the nucleotide -base sequence of a gene on a DNA molecule. 2- Chromosomal mutations are changes in the structure or the numbers of chromosomes (a gain or loss). Gene mutations involve changes in the nucleotide sequence of the DNA molecule. 3-A gene mutation is a permanent change in the DNA sequence that makes up a gene. Mutations range in size from a single DNA building block (DNA base) to a large segment of a chromosome while a chromosomal mutation is a mutation involving a long segment of DNA, it is a any change in the structure or arrangement of the chromosomes. These mutations can involve deletions, insertions, or inversions of sections of DNA. In some cases, deleted sections may attach to other chromosomes, disrupting both the chromosomes that loses the DNA and the one that gains it.It is also referred to as a chromosomal rearrangement 4-gene mutation is just a substitute in any old random nucleotide for any old random nucleotide chromosome mutation is missing of chromosome or +1 chromosome (down's syndrome).
mutations
Gene mutations that occur at a single point in the DNA sequence are called point mutations. These mutations can involve substitutions of one nucleotide for another (missense mutation), insertion of an extra nucleotide (insertion mutation), or deletion of a nucleotide (deletion mutation). Point mutations can have various effects on the resulting protein, ranging from no impact to severe functional changes.
Epigenetics refers to changes in gene expression that do not involve changes to the underlying DNA sequence, while mutations are changes in the DNA sequence itself. Epigenetic changes can be reversible and can affect how genes are turned on or off, influencing gene expression and inheritance without altering the DNA sequence. Mutations, on the other hand, are permanent changes to the DNA sequence that can lead to altered gene function and inheritance patterns.
Gene mutations can best be described as changes in the DNA sequence of a gene. These changes can result in altered proteins being produced, impacting an individual's traits or causing genetic disorders. Mutations can occur spontaneously or be induced by external factors such as radiation or chemicals.
Cystic fibrosis (CF) is primarily caused by mutations in the CFTR gene, which encodes a protein that regulates salt and water transport in cells. A DNA fingerprint from a person with CF would likely show specific mutations in the CFTR gene, such as the common F508del deletion, whereas a person without CF would have a normal CFTR gene sequence. While the overall DNA fingerprint may appear similar, the presence of these specific mutations distinguishes individuals with CF from those without the condition.
Successful mutations will persist. Mutations usually occur during replication. Some mutations will flourish depending on environmental factors.
Some common DNA mutations directly linked to inherited diseases include the CFTR gene mutation in cystic fibrosis, the BRCA gene mutations in breast and ovarian cancers, and the HTT gene mutation in Huntington's disease. These mutations can be inherited from one or both parents and increase the likelihood of developing the associated disease.
Possible factors that could prevent DNA from producing proteins coded by a gene include mutations in the gene sequence, epigenetic modifications that block gene expression, improper regulatory signals, or environmental factors that disrupt the transcription or translation process.