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Would receiving breast cancer chemo cocktail Cyclophosphamide Doxorubicin Docetaxel Herceptin through port threaded to jugular vein vs subclavian vein had bearing on brain chemical level alteration?
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Solubility of docetaxel in Ethyl lactate?
docetaxel
Why tween 80 is used in formulation of docetaxel injection?
Docetaxel is practically insoluble in water. Tween is added to improve itssolubility.
What is the emetogenic and tissue damage potential of docetaxel?
Not a highly emetogenic drug. no prophylactic antiemetic required. and is not related with significant tissue damage.
What is the cost of docetaxel?
The cost of Taxotere treatment is $AU 18,286 on average per patient, according to Medical News Today. This equals about $US 16,263.
What is platinum based doublet?
It is the combination of platinum-based (cisplatin, carboplatin) chemotherapy AND docetaxel, paclitaxel, vinorelbine, gemcitabine or irinotecan ... based chemotherapy. ...platinum-doublet chemotherapy (Carboplatin AUC 6+Paclitaxel 200mg/m2 day1 Q3w, Cisplatin 80mg/m2 day1+Irinotecan 60mg/m2 day1,8,15 Q4W, Cisplatin 80mg/m2 day1+Vinorelbine 25mg/m2 day1,8 Q3W, Cisplatin 80mg/m2 + Docetaxel 60mg/m2 day1 Q3W, or Cisplatin 80mg/m2 day1+Gemcitabine 1,000mg/m2 day1, 8 Q3W) up to 6 cycles ...
What has the author Amanda Louise Dunne written?
Amanda Louise Dunne has written the novel "The Walls Are Talking" which tells the story of a woman who discovers a hidden mural in her new home, revealing secrets about its past.
Does vitamin B6 help combat chemotherapy damage?
Vitamin B6 can help prevent peripheral neropathy caused by taxane based chemotherapy. Taxane based chemo, such as paclitaxel (Taxol) and docetaxel (Taxotere), can cause numbness and tingling in the hands and feet (peripheral neuropathy) because it can cause degeneration to the nerve cells. One of the many functions of Vitamin B6 is neurotransmitter synthesis, thus combating the effects of chemo. The following researched based report discusses this topic in more detail.
How was Taxol discovered?
Taxol belongs to a class of chemotherapy drugs called plant alkaloids. Plant alkaloids are made from plants. The vinca alkaloids are made from the periwinkle plant (catharanthus rosea). The taxanes are made from the bark of the Pacific Yew tree (taxus). The vinca alkaloids and taxanes are also known as antimicrotubule agents. The podophyllotoxins are derived from the May Apple plant. Camptothecan analogs are derived from the Asian "Happy Tree" (Camptotheca acuminata). Podophyllotoxins and camptothecan analogs are also known as topoisomerase inhibitors. The plant alkaloids are cell-cycle specific. This means they attack the cells during various phases of division. * Vinca alkaloids: Vincristine, Vinblastine and Vinorelbine. * Taxanes: Taxol and Docetaxel. * Podophyllotoxins: Etoposide and Tenisopide. * Camptothecan analogs: Irinotecan and Topotecan. Antimicrotubule agents (such as Taxol), inhibit the microtubule structures within the cell. Microtubules are part of the cell's apparatus for dividing and replicating itself. Inhibition of these structures ultimately results in cell death. I hope this helps Please understand that drugs are "discovered" every minute and go through many levels of testing and departments of our great "laws for processes" in order to be introduced to the medical world. It is possible that the drug companies will not release any further information then the above facts in order to protect the creative employee or other persons involved in its creation.
How do you get ovarian cancer?
Ovarian cancer is caused by cells of the ovaries not doing the "job" they are supposed to do, and instead revert all of their energy into uncontrolled reproduction. This is true of all cancers. The reason it is so hard for the body to fight off cancer is because it is actually the body's own cells that cause the problem. When cells grow at an uncontrolled rate, it becomes difficult for the other healthy cells to perform their function due to the fact they become outnumbered by the cancerous cells. Eventually these cancerous cells can enter the blood stream or lymph system and spread to other organs. Cancer usually causes a patient's demise due to the fact it causes organs to shut down, because all the energy is spent on uncontrolled cell growth, rather than cell function.
