Gas gangrene is a potentially deadly form of tissue death (gangrene).
See also: Necrotizing subcutaneous infection
Alternative NamesTissue infection - Clostridial; Gangrene - gas; Myonecrosis; Clostridial infection of tissues
Causes, incidence, and risk factorsGas gangrene is rare in the United States. The condition is most often caused by a bacteria called Clostridium perfringens.However, it also can be caused by Group A streptococcus. Staphylococcus aureus and Vibrio vulnificus can cause similar infections.
Clostridium is present in most environments. As the bacteria grow, they can produce gas in body tissues and produce many different toxins that can damage tissues. Under low-oxygen (anaerobic) conditions, Clostridium produces toxins that cause tissue death and related symptoms.
Gas gangrene generally occurs at the site of trauma or a recent surgical wound. The onset of gas gangrene is sudden and dramatic. About 1 in 5 cases occur without an irritating event. Patients who develop this disease in this manner often have underlying blood vessel disease (atherosclerosis or hardening of the arteries), Diabetes, or colon cancer.
Clostridium bacteria produce many different toxins, four of which (alpha, beta, epsilon, iota) can cause potentially deadly syndromes. The toxins cause damage to tissues, blood cells, and blood vessels.
SymptomsThe site of infection becomes inflamed with a pale to brownish-red and very painful tissue swelling. If you press on the swollen tissue with your fingers, you may feel gas as a crackly sensation. The edges of the infected area expand so quickly that changes can be seen over a few minutes. The involved tissue may be completely destroyed.
Symptoms include:
Note: Symptoms usually begin suddenly and quickly worsen.
If the condition is not treated, the person can develop shock with decreased blood pressure (hypotension), kidney failure, coma, and finally death.
Signs and testsThe person may be in shock. A health care professional might feel air in the tissues (crepitus).
The person will need to have surgery quickly to remove dead, damaged, and infected tissue (debridement). Surgical removal (amputation) of an arm or leg may be needed to control the spread of infection. Often this must occur before all diagnostic test results are available.
Patients should get antibiotics, preferably penicillin-type with clindamycin. Initially, patients receive antibiotics through a vein (intravenously). Some people may need analgesics to control pain. Doctors have tried hyperbaric oxygen for this condition, with varying degrees of success.
Expectations (prognosis)Gas gangrene is progressive and often fatal.
ComplicationsThis is an emergency condition requiring immediate medical attention.
Call your heath care provider if you have signs of infection around a skin wound. Go to the emergency room or call the local emergency number (such as 911), if you have symptoms of gas gangrene.
PreventionClean any skin injury thoroughly. Watch for signs of infection (such as redness, pain, drainage, or swelling around a wound), and consult your health care provider promptly if these occur.
ReferencesBartlett JG. Clostridial infections. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 319.
Gas gangrene is a potentially deadly form of tissue death (gangrene).
See also: Necrotizing subcutaneous infection
Alternative NamesTissue infection - Clostridial; Gangrene - gas; Myonecrosis; Clostridial infection of tissues
Causes, incidence, and risk factorsGas gangrene is rare in the United States. The condition is most often caused by a bacteria called Clostridium perfringens.However, it also can be caused by Group A streptococcus. Staphylococcus aureus and Vibrio vulnificus can cause similar infections.
Clostridium is found most everywhere. As the bacteria grow inside the body, it makes gas and harmful substances (toxins) that can damage body tissues, cells, and blood vessels.
Gas gangrene develops suddenly. It usually occurs at the site of trauma or a recent surgical wound. About 1 in 5 cases occur without an irritating event. Patients most at risk for this usually have underlying blood vessel disease (atherosclerosis or hardening of the arteries), diabetes, or colon cancer.
SymptomsGas gangrene causes very painful swelling. The skin turns pale to brownish-red. If you press on the swollen area with your fingers, you may feel gas as a crackly sensation. The edges of the infected area grow so quickly that changes can be seen over a few minutes. The area may be completely destroyed.
Symptoms include:
Note: Symptoms usually begin suddenly and quickly worsen.
If the condition is not treated, the person can develop shock with decreased blood pressure (hypotension), kidney failure, coma, and finally death.
Signs and testsThe health care provider will perform a physical exam. This may reveal signs of shock.
Tests that may be done include:
Surgery is needed quickly to remove dead, damaged, and infected tissue. This is called debridement.
Surgical removal (amputation) of an arm or leg may be needed to control the spread of infection. Amputation sometimes must be done before all test results are available.
You will also be given antibiotics, usually penicillin-type and clindamycin. These medicines will be given through a vein (intravenously). Doctors have tried hyperbaric oxygen for this condition, with varying degrees of success. Pain medicines may also be prescribed.
Expectations (prognosis)Gas gangrene usually begins suddenly and quickly gets worse. It is often deadly.
ComplicationsThis is an emergency condition requiring immediate medical attention.
Call your heath care provider if you have signs of infection around a skin wound. Go to the emergency room or call the local emergency number (such as 911), if you have symptoms of gas gangrene.
PreventionClean any skin injury thoroughly. Watch for signs of infection (such as redness, pain, drainage, or swelling around a wound), and consult your health care provider promptly if these occur.
ReferencesGerding DN, Johnson S. Clostridial infections. In: Goldman L, Ausiello D, eds.Cecil Medicine. 24th ed. Philadelphia, Pa: Saunders Elsevier; 2011:chap 304.
Reviewed ByReview Date: 12/06/2011
Linda J. Vorvick, MD, Medical Director, MEDEX Northwest Division of Physician Assistant Studies, University of Washington, School of Medicine. Jatin M. Vyas, MD, PhD, Assistant Professor in Medicine, Harvard Medical School; Assistant in Medicine, Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
Gangrene is the scientific name.
1
Yes
Many people can only live with gangrene no longer than two months. This is because the infection eats away at your body. However, gangrene is no longer a common health ailment.
People in car collisions, involved in natural disasters, and drugies.
Gas Gangrene is in the air if not on your body
clostridium gas gangrene is an illness due to Clostridium clostridium perfringens is a bacteria and can be at the origin of gas gangrene
Gangrene is the scientific name.
maybe
No, it may progress to the point of amputation. Gangrene prouces a gas which permeates the healthy tissues.
1
Yes
Yes.Gangrene is the death of an area of the body usually due to loss of blood supply. Gangrene can be caused from a bacterial infection that has not been treated; this is wet gangrene. Or, gangrene can be caused by a decrease in blood flow to an area of the body where the tissue in this part of the body has been injured or diseased; this is dry gangrene.
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about 25,000 people die from gangrene a year
There is three different types which are wet,dry,gas(:
Gangrene claims about 25,000 lives each year