NO. 2-wheel and 4-wheel drive transmissions are DIFFERENT. They will not interchange.
the 2wd turbo 350 has a longer tail shaft NEW ANSWER: The center shaft in a 4x4 transmission is longer then a 2 wheel drive trans. The reason is that it has a transfur case on the end of it, and the center shaft must fit into the transfur case to make it work.
No. 2 and 4-wheel drive transmissions are different. Will not interchange.
turbo 350
The 2009 Lexus IS-350 has rear wheel drive.
The 2013 Lexus IS-350 has rear wheel drive.
The 2011 Lexus IS-350 has rear wheel drive.
The 2010 Lexus IS-350 has rear wheel drive.
The 2008 Lexus IS-350 has rear wheel drive.
The 2006 Lexus IS-350 has rear wheel drive.
The 2014 Lexus IS-350 has rear wheel drive.
The 2007 Lexus IS-350 has rear wheel drive.
The 2012 Lexus IS-350 has rear wheel drive.