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In a broad sense the Renaissance didn't end, it spread across Western Europe and fed into a succession of artistic and intellectual phenomena. But central & northern Italy's loss of cultural leadership after the 15th century doubtless owes much to the upheavals and economic downturn following the French invasion of 1494 and the subsequent 65 years of intermittent Valois-Habsburg war, as well as to the shift of economic, cultural & political primacy to north-western Europe following the discovery of the Americas, the Reformation and the rise of national states.

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Q: What ended the Renaissance?
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