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Could be,

spark plug(s),

contaminated fuel (water),

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9y ago
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Q: What might cause a sporadic misfire on a 99 GMC 6500 with 454 gas engine?
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What is wrong with the engine when the engine light on the dash board keeps flashing?

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Can bad timing cause your car to idle rough and vibrate badly while in gear?

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The shaking wheel part suggest that there might be an engine misfire, the engine light on suggests that the computer is trying to tell you what's wrong. Connect the engine to a diagnostic computer to see what's going on. The computer can often give you hints to the real problem.