route 66
Take I-70 EAST to I-55 SOUTH via I-270 SOUTH in suburban St. Louis, Missouri. (EXIT 232B off I-70 to get onto I-270 SOUTH, then EXIT 1A off I-270 to get onto I-55 SOUTH to MEMPHIS.)Take I-55 SOUTH to Memphis.
E842 is the best route across. SS16 to A14 connects to that.
There are two basic choices: north and east on I-40 or south and east on I-10 and I-20. Both are about the same distance and take about the same amount of time. It becomes a matter of what you want to see and do along the way. The southern route requires crossing the entire width of Texas and the drive from El Paso to Dallas is particularly barren. I would choose the northern route, preferring stops in Memphis and Nashville over Jackson and Birmingham.
The best route to drive from Chicago to Pittsburgh is to take Interstate 90 East to Interstate 80 East. This route is the most direct and efficient way to reach Pittsburgh from Chicago by car.
Personally I'd probably use the I-80 route.
a popular cattle drive route in the years after the Civil War
The quickest and shortest route is I-5 North.
Take I-75 NORTH to I-24 WEST to CHATTANOOGA and NASHVILLE at EXIT 2 in Tennessee.Take I-24 WEST to I-40 WEST to MEMPHIS via I-440 (EXIT 53 off I-24).Take I-40 WEST to MEMPHIS.
The best route for a drive from Salt Lake City to Denver is typically via Interstate 80 East and Interstate 25 South. This route is the most direct and commonly used for traveling between the two cities.
The best route for a drive from Salt Lake City to Phoenix is to take Interstate 15 South. This route is the most direct and efficient, taking you through scenic areas and major cities along the way. It is approximately a 10-hour drive covering a distance of about 650 miles.
The best route to drive from Phoenix to Salt Lake City is to take Interstate 17 North to Interstate 40 East, then merge onto Interstate 15 North. This route is approximately 700 miles and takes about 10-11 hours to drive, depending on traffic and weather conditions.