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Every amino acid has 5 main parts to it, a carbon in the middle bonded to a Hydrogen, a variable group, a carboxyl group and an amine group. The important 2 for bonding are the carboxyl group which has a carbon double bonded to an Oxygen and a single bond to a hydroxyl group. The amine group is a nitrogen group bonded to 2 hydrogen.

In order to bond, the amine group of one amino acid has to align with the carboxyl group of another. Then, the hydroxyl group of the carboxyl will react with a hydrogen on the amino group to release a water in a process known as dehydration synthesis. As the water gets removed, the nitrogen from the amine group bonds to the carbon in the carboxyl, completing a peptide bond between our 2 amino acids. These peptide bonds can occur at either end of an amino acid, allowing us to make long chains of daunting length.

Since amino acid sequences are often so long, the structure can easily be affected by other amino acids far away in the linear chain. On the small scale, this allows for amino acid chains that either form helices or pleated sheets. On a larger scale, the chains can make complex bonding patterns that fold back, twist, turn, and allow for the basis of all life!
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How are amino acids joined to protein?

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