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Yes - there is a limit to how big or small a cell can be.

The upper limit is mostly a factor of the surface area to volume ratio. If the volume is much larger than the surface area, especially in a unicellular organism, then substances would take far too long to travel from the outside of the cell to the centre, or from inside the cell to the outside. This would create problems with supplying the inside of the cell with oxygen and food, and with removing waste products from the cell.

The lower limit (how small a cell can be) is less easily explained. It may be that a cell must be large enough to contain the essential components it needs for life (eg. components involved in energy conversion/production). So for example, a cell could not be smaller than an oxygen or water molecule because it would need to be large enough for these to enter and be used by the cell.

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12y ago

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