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What happens to acetyl CoA if its not needed in the Krebs cycle?

Acetyl CoA is multifunctional; it can be used to produce fat or ATP. If the body needs energy, acetyl CoA enters the Krebs cycle. If the body doesn't need energy, acetyl CoA is channelled into an anabolic pathway that synthesizes lipids as a way of storing large amounts of energy as fat.


How carbs proteins and fats can be converted to pyruvate glucose andor acetyl CoA and get used to make ATP or stored as fat?

Carbohydrates are broken down into glucose, which can be converted into pyruvate through glycolysis. Proteins are broken down into amino acids, some of which can enter the glycolytic pathway to generate pyruvate. Fats are broken down into fatty acids, which can be converted into acetyl CoA through beta-oxidation. Both pyruvate and acetyl CoA can enter the citric acid cycle to generate ATP. Excess glucose, pyruvate, and acetyl CoA can be converted into fat and stored for energy reserves.


What polysaccharide is stored in the liver when excess glucose is in the bloodstream?

Glucose has many fates in the human body depending on whether the body is in a fasted or fed state. It is important to note that glucose is the main and primary compound used by all cells to produce energy. Some cells, namely nervous tissue and mature red blood cells use ONLY glucose to provide energy. If a meal with excessive carbohydrates is consumed, after digestion the excess glucose is first converted into a storage carbohydrate called glycogen. Glycogen is stored in skeletal muscles and liver cells. In muscles it serves as a ready store of energy for muscle contractions and in liver cells it can be readily reconverted into glucose and used in periods of fasting (during sleep or between meals to provide and sustain energy). However, if there is excessive glucose in the body and the muscle and liver tissues have made its maximal amount of glycogen, the excess glucose is converted to FAT! Fat (namely triacylglycerol) is made of two compounds: fatty acids and glycerol - both which can be synthesized from glucose breakdown. NOTE: Fatty acids, a main component of triacylglycerol are made from a compound called acetyl CoA. Under normal circumstances glucose is converted to acetyl CoA, but it enters a pathway in cells called the Krebs Cycle where it is degraded to produce energy. However, when there is excessive glucose and the body has already made its fill of glycogen, glucose is broken down to acetyl coA in the liver where it goes to produce fatty acids and subsequently fat! Exactly how is this done? For the biochemists out there: Malonly CoA is the direct precursor for fatty acid synthesis. Acetyl coA is converted to malonly coA via the enzyme acetyl coA carboxylase - this is the committed step in fatty acid synthesis. This enzyme is activated by high amounts of citrate, a by product of the Krebs Cycle. So an excessive amounts of glucose after maxed out glycogen production = high acetyl coA + high citrate. High citrate activates acetyl coA carboxylase which commits acetyl coA to fat production via synthesis of malonyl coA.


From where does oxaloacetate come during kreb's cycle?

Oxaloacetate is initially produced from pyruvate by pyruvate carboxylase in the mitochondria. It is a critical component of the Krebs cycle as it combines with acetyl-CoA to form citrate, starting the cycle.


When cells do not need energy when ATP is abundant Acetyl CoA can be converted to?

Glycogen first. 150 grams in Liver and 150 grams in muscles, aproximately. Then to Fat. Which is stored in body. Body has a very large resevre of Fat and as on today, obesity is one of the major problem for billions of people.

Related Questions

What happens to acetyl-CoA if cell already has sufficient quantities of ATP?

The acetyl-CoA is diverted to Fat Synthesis (energy storage).Read more: If_a_cell_already_has_a_large_supply_of_ATP_the_acetyl-CoA_is_funneled_to_make


What molecules are produced from excess fat breakdown?

Mostly free fatty acids and triglycerides.


What molecule is produced from excess fat breakdown?

Excess fat breakdown produces molecules called fatty acids and glycerol. Fatty acids can be used for energy production or stored as triglycerides in adipose tissue, while glycerol can be converted to glucose through a process called gluconeogenesis.


What happens to acetyl CoA if its not needed in the Krebs cycle?

Acetyl CoA is multifunctional; it can be used to produce fat or ATP. If the body needs energy, acetyl CoA enters the Krebs cycle. If the body doesn't need energy, acetyl CoA is channelled into an anabolic pathway that synthesizes lipids as a way of storing large amounts of energy as fat.


When protein consumption is in excess of body needs and energy needs are met the excess amino acids are metabolized and the energy in the molecule is?

Our bodies cannot store excess protein once it is consumed, so the excess amino acids are converted to carbon skeletons that are turned into glucose or fat and then stored as fat or metabolized for energy needs. **stored as glycogen & fat** jmata~


What happens to amino acids inside the liver?

They are broken down into urea then carried via blood to the kidneys and the excreted as urine


When protein consumption is in excess of body needs and energy needs are met the excess amino acids are metabolized and the energy in the molecule is what?

Our bodies cannot store excess protein once it is consumed, so the excess amino acids are converted to carbon skeletons that are turned into glucose or fat and then stored as fat or metabolized for energy needs. **stored as glycogen & fat** jmata~


How is lipid synthesized from the extra glucose molecules you accumulate after carbo loading?

Glucose is broken down into acetyl-coenzyme A (glycolysis). In liver or adipose tissue acetyl-coA can form lipids. Insulin is one of the most important factors, it is released from pancreas after sugar intake and stimulates the formation of fat.


What happen when the body is supply with more energy that it burn?

It stores the excess energy in the form of fat cells, to be metabolized when needed at a later time.


What is the medical terminology breakdown of the word hypercapnia?

hyper- excess -capnia indicating carbon dioxide


How carbs proteins and fats can be converted to pyruvate glucose andor acetyl CoA and get used to make ATP or stored as fat?

Carbohydrates are broken down into glucose, which can be converted into pyruvate through glycolysis. Proteins are broken down into amino acids, some of which can enter the glycolytic pathway to generate pyruvate. Fats are broken down into fatty acids, which can be converted into acetyl CoA through beta-oxidation. Both pyruvate and acetyl CoA can enter the citric acid cycle to generate ATP. Excess glucose, pyruvate, and acetyl CoA can be converted into fat and stored for energy reserves.


Reuptake refers to the?

reabsorption of excess neurotransmitter molecules by a sending neuron