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The determination of whether a synapse is excitatory or inhibitory is based on the type of neurotransmitter released at the synapse. Excitatory synapses release neurotransmitters that promote the firing of the receiving neuron, while inhibitory synapses release neurotransmitters that prevent the firing of the receiving neuron.

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What is the difference between the way excitatory and inhibitory transmitters work?

As a rule more than one presynaptic action potential is needed to fire the postsynaptic neuron or muscle so that the trigger to initiate an action potential are either many subthreshold local potentials from different sources or from the same neuron received within a short period of time. The first case is called spatial summation and the second case is called temporal summation. Whether a postsynaptic potential (another term for a local potential) is excitatory or inhibitory depends on what ion channels are affected by the transmitter released from the presynaptic vesicles.


The nerve and identify he parts?

Do you want to know the parts of a nerve?Synapses are the junctions formed with other nerve cells where the presynaptic terminal of one cell comes into 'contact' with the postsynaptic membrane of another. It is at these junctions that neurons are excited, inhibited, or modulated. There are two types of synapse, electrical and chemical.Electrical synapses occur where the presynaptic terminal is in electrical continuity with the postsynaptic. Ions and small molecules passing through, thus connecting channels from one cell to the next, so that electrical changes in one cell are transmitted almost instantaneously to the next. Ions can generally flow both ways at these junctions i.e. they tend to be bi-directional, although there are electrical junctions where the ions can only flow one way, these are know as rectifying junctions. Rectifying junctions are used to synchronise the firing of nerve cells.Chemical synaptic junction is more complicated. The gap between the post- and presynaptic terminals is larger, and the mode of transmission is not electrical, but carried by neurotransmitters, neuroactive substances released at the presynaptic side of the junction. There are two types of chemical junctions. Type I is an excitatory synapse, generally found on dendrites, type II is an inhibitory synapse, generally found on cell bodies. Different substances are released at these two types of synapse. The direction of flow of information is usually one way at these junctions.Each terminal button is connected to other neurons across a small gap called a synapse. The physical and neurochemical characteristics of each synapse determines the strength and polarity of the new input signal. This is where the brain is the most flexible, and the most vulnerable. Changing the constitution of various neurotransmitter chemicals can increase or decrease the amount of stimulation that the firing axon imparts on the neighbouring dendrite. Altering the neurotransmitters can also change whether the stimulation is excitatory or inhibitory.


What takes place in the synapse?

Chemical synapses are specialized junctions through which neurons signal to each other and to non-neuronal cells such as those in muscles or glands. Chemical synapses allow neurons to form interconnected circuits within the central nervous system. They are thus crucial to the biological computations that underlie perception and thought. They provide the means through which the nervous system connects to and controls the other systems of the body, for example the specialized synapse between a motor neuron and a muscle cell is called a neuromuscular junction. The adult human brain has been estimated to contain from 1014 to 5 × 1014 (100-500 trillion) synapses.[citation needed] The word "synapse" comes from "synaptein", which Sir Charles Scott Sherrington and colleagues coined from the Greek "syn-" ("together") and "haptein" ("to clasp"). Chemical synapses are not the only type of biological synapse: electrical and immunological synapses exist as well. Without a qualifier, however, "synapse" commonly refers to a chemical synapse. Wikipedia


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Related Questions

What determines whether the response of a receiving neuron is excitatory or inhibitory?

The type of neurotransmitter.


What neurotransmitters are exclusively inhibitory?

The terms antagonist/agonist only apply to 'exogenous' compounds, namely drugs and toxins, and not neurotransmitters - which are commonly classed according to whether they are excitatory or inhibitory. Examples of a the latter include GABA and glycine.


What determines whether a neurotransmitter will have an inhibitory excitatory effect?

How a neurotransmitter interacts with the receptors determines its effects. They activate receptors to perform specific functions in the body.the type of receptor


What determines if an action potential is initiated in the postsynaptic neuron?

Every time neurotransmitter is released from the presynaptic neuron it generates an excitatory post synaptic potential(EPSP) in the postsynaptic neuron. When the EPSP is greater than the threshold for excitation an action potential is generated.


What is the difference between the way excitatory and inhibitory transmitters work?

As a rule more than one presynaptic action potential is needed to fire the postsynaptic neuron or muscle so that the trigger to initiate an action potential are either many subthreshold local potentials from different sources or from the same neuron received within a short period of time. The first case is called spatial summation and the second case is called temporal summation. Whether a postsynaptic potential (another term for a local potential) is excitatory or inhibitory depends on what ion channels are affected by the transmitter released from the presynaptic vesicles.


What happens when an impulse arrives at a synapse?

The electrical impulse causes chemicals called neurotransmitters to be released from the axon terminals of the pre-synaptic neuron which diffuseacross the synaptic cleft and fit into receptors on the post-synaptic neuron.In an excitatory synapse, the presence of the neurotransmitters in the receptors of ligand-gated ion pores cause those pores to open and allow sodium ions into the post-synaptic neuron, which results in an electrotonic signal being conducted down the dendrite and soma to the axon hillock, which may initiate an action potential in the axon if enough signals are summed up at the axon hillock to reach a trigger value.


How does a neuron decide whether or not to produce action potentials?

A neuron decides whether or not to produce an action potential by a summation of excitatory and inhibitory signals at the trigger point of the neuron, the axon hillock (or, the initial segment of the axon immediately following the axon hillock), plus a sufficient density of voltage-gated sodium ion pores at the trigger point.Neurons can receive both excitatory and inhibitory inputs at the same time, and if a confluence of those multiple signals at the axon hillock/initial axon segment (or alternatively, an occasion of sufficiently quickly repeated excitatory signals) sums to yield a membrane potential there of about -55 mv, this will cause the large number of voltage-gated sodium ion pores present there to open, allowing a sufficient influx of sodium ions to raise the membrane potential momentarily higher, which depolarizes adjacent regions of the axon, allowing more voltage-gated ion pores to open, allowing more sodium ions in; these actions repeat and continue along the axon, achieving the action potential.It's important to understand that although the level of the summation of signal voltages is the trigger for the action potential, the initial firing of the action potential could not occur if there wasn't a sufficient density of voltage-gated sodium ion pores at the trigger point to allow sufficient sodium ions in to cause the membrane potential in adjacent regions to be high enough to open theirv-gated Na ion pores, so that the action potential could continue to propagate along the axon.


The nerve and identify he parts?

Do you want to know the parts of a nerve?Synapses are the junctions formed with other nerve cells where the presynaptic terminal of one cell comes into 'contact' with the postsynaptic membrane of another. It is at these junctions that neurons are excited, inhibited, or modulated. There are two types of synapse, electrical and chemical.Electrical synapses occur where the presynaptic terminal is in electrical continuity with the postsynaptic. Ions and small molecules passing through, thus connecting channels from one cell to the next, so that electrical changes in one cell are transmitted almost instantaneously to the next. Ions can generally flow both ways at these junctions i.e. they tend to be bi-directional, although there are electrical junctions where the ions can only flow one way, these are know as rectifying junctions. Rectifying junctions are used to synchronise the firing of nerve cells.Chemical synaptic junction is more complicated. The gap between the post- and presynaptic terminals is larger, and the mode of transmission is not electrical, but carried by neurotransmitters, neuroactive substances released at the presynaptic side of the junction. There are two types of chemical junctions. Type I is an excitatory synapse, generally found on dendrites, type II is an inhibitory synapse, generally found on cell bodies. Different substances are released at these two types of synapse. The direction of flow of information is usually one way at these junctions.Each terminal button is connected to other neurons across a small gap called a synapse. The physical and neurochemical characteristics of each synapse determines the strength and polarity of the new input signal. This is where the brain is the most flexible, and the most vulnerable. Changing the constitution of various neurotransmitter chemicals can increase or decrease the amount of stimulation that the firing axon imparts on the neighbouring dendrite. Altering the neurotransmitters can also change whether the stimulation is excitatory or inhibitory.


How could one determine whether a sample of aspirin is pure or not?

The determination is by chemical analysis.


What determines whether a neuron will have an action potential triggered?

The effect upon the target neuron is determined not by the source neuron or by the neurotransmitter, but by the type of receptor that is activated. A neurotransmitter can be thought of as a key, and a receptor as a lock: the same type of key can here be used to open many different types of locks. Receptors can be classified broadly as excitatory(causing an increase in firing rate),inhibitory(causing a decrease in firing rate), or modulatory(causing long-lasting effects not directly related to firing rate).


What is a value judgment?

It is a determination of whether something is good or bad based on your personal experience and standards.


Who makes the final determination as to whether a work request is urgent or rountine?

customer service unit