In eukaryotes, gene expression regulation is more complex and involves multiple levels of control, such as chromatin remodeling, transcription factors, and post-transcriptional modifications. Prokaryotes, on the other hand, have simpler regulation mechanisms, mainly involving operons and transcription factors.
Eukaryotes have additional complexity in post-transcriptional processing, such as alternative splicing, intron removal, and mRNA editing, which can lead to a greater degree of regulation and diversity in gene expression compared to prokaryotes. Additionally, eukaryotic mRNA processing occurs in the nucleus before export to the cytoplasm, providing an additional layer of control.
Sigma factors are specific proteins in prokaryotes that help RNA polymerase bind to the promoter region of a gene to initiate transcription. Transcription factors, on the other hand, are proteins in eukaryotes that regulate gene expression by binding to specific DNA sequences and influencing the activity of RNA polymerase. In summary, sigma factors are specific to prokaryotes and help initiate transcription, while transcription factors are found in eukaryotes and regulate gene expression.
In prokaryotes, the promoter is made up of two sequences at -10 and -35. Eukaryotic promoters are diverse and difficult to characterize, they lie upstream of the gene and have regulatory elements that are several kilobases away from the start site.
The main purpose of gene regulation in eukaryotes is to control which genes are turned on or off in response to internal and external signals. This allows for precise control of gene expression, ensuring that the right genes are expressed at the right time and in the right amount for proper cell function and development.
Prokaryotes have been around for 2 billion more years than eukaryotes so have a much wider diversity. Some prokaryotes can live in extreme environments, so there is a lot to learn from them. Plus the wide range of prokaryotes have not been cataloged while the majority of eukaryotic species have likely been discovered.
In prokaryotes, gene expression can be regulated directly at the level of transcription through operons, where multiple genes are controlled by a single promoter. This type of regulation is not as common in eukaryotes, where gene expression is typically regulated at multiple levels, including transcription, RNA processing, translation, and post-translational modifications. Additionally, prokaryotes lack the complexity of chromatin structure found in eukaryotic cells, which can also impact gene expression regulation.
In prokaryotes, DNA is stored in the cytoplasm. also prokaryotes have no nucleus In prokaryotes, transcription and translation happen at the same time.
Eukaryotes have additional complexity in post-transcriptional processing, such as alternative splicing, intron removal, and mRNA editing, which can lead to a greater degree of regulation and diversity in gene expression compared to prokaryotes. Additionally, eukaryotic mRNA processing occurs in the nucleus before export to the cytoplasm, providing an additional layer of control.
Sigma factors are specific proteins in prokaryotes that help RNA polymerase bind to the promoter region of a gene to initiate transcription. Transcription factors, on the other hand, are proteins in eukaryotes that regulate gene expression by binding to specific DNA sequences and influencing the activity of RNA polymerase. In summary, sigma factors are specific to prokaryotes and help initiate transcription, while transcription factors are found in eukaryotes and regulate gene expression.
In prokaryotes, the promoter is made up of two sequences at -10 and -35. Eukaryotic promoters are diverse and difficult to characterize, they lie upstream of the gene and have regulatory elements that are several kilobases away from the start site.
They are similar because they use the same bonding techniques. However are different because eukaryotic cells have a nucleus creating a much more complex system, therefore they have more DNA than prokaryotic cells.
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The main purpose of gene regulation in eukaryotes is to control which genes are turned on or off in response to internal and external signals. This allows for precise control of gene expression, ensuring that the right genes are expressed at the right time and in the right amount for proper cell function and development.
Prokaryotes have been around for 2 billion more years than eukaryotes so have a much wider diversity. Some prokaryotes can live in extreme environments, so there is a lot to learn from them. Plus the wide range of prokaryotes have not been cataloged while the majority of eukaryotic species have likely been discovered.
Gene regulation in eukaryotes is important because it allows cells to control when and how genes are expressed, enabling them to respond to internal and external signals appropriately. This regulation ensures that only the necessary genes are turned on at the right time and in the right amount, which is crucial for processes such as development, differentiation, and maintaining cellular homeostasis. Dysregulation of gene expression can lead to diseases such as cancer and developmental disorders.
Cis genes are regulated and expressed on the same chromosome they are located on, while trans genes are regulated and expressed on a different chromosome. This difference in regulation can impact how genes interact with each other and influence their expression levels.
Gene expression can be controlled at any of several stages, which we divide broadly into transcription, processing and translation. Transcription often is controlled at the stage of initiation, or at termination but usually not controlled at elongation. In eukaryotic cells, processing of the RNA product may be regulated at the stages of modification, splicing, transport, or stability. Translation may be regulated, usually at the stages of initation and termination just like transcription. Gene expression can be controlled at any of several stages, as during transcription, processing and translation. Transcription often regulated at initiation and termination but elongation is usually not regulated. In eukaryotes cells, processing of the RNA product may be regulated at the stages of modification, splicing, transport, or at stability. Translation may be regulated at initiation and termination just like transcription.