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A and B are antigens that are on the surface of red blood cells. People have one, both, or none. If you don't naturally produce the antigen, your body's white blood cells will attack and destroy red blood cells that carry them.

So if a person with type A blood is injected with type B blood, the body of that person will attack the type-B blood cells.

O- is called the universal donor, because it lacks all antigens. So no one's body will recognize it as foreign. Because of this, hospitals often administer O- blood to patients with a critical need, because there isn't enough time to determine blood type of the patient.

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Q: What blood product has the least concern with ABO compatibility?
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