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What determines whether or not a specific tRNA can bind to an mRNA?
Wiki User
∙ 14y ago
Messenger RNA (mRNA) is composed of long strings of nucleotides. These nucleotides are further arranged into groups of three, called codons. There are 64 possible combinations of codons, and they code for 20 amino acids in all (some amino acids are coded for by more than one codon.)
Transfer RNA (tRNA) is composed of the same nucleotides as mRNA. One specific location on a tRNA molecule, known as the anticodon, is capable of linking to the codon on the mRNA. This is determined by the same rules that allow these bonds to form in other DNA/RNA. Uracil may link with Adenine, and Cytosine may link with Guanine. U and A form two hydrogen bonds, while C and G form three.
Thus, a tRNA's anticodon (and, more specifically, the rules governing the bonds between nucleotides) is what determines whether it will bind to an mRNA codon, bringing with it the amino acid that the mRNA codon codes for.
Wiki User
∙ 14y ago
Wiki User
∙ 13y agoThe anticodon.
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Where do Ribosomes bind on mRNA?
On the GGAGG sequence.
What is anti sense therapy?
Anti-sense therapy refers to inserting cDNA sequences to bind mRNA's (through complementarity thus preventing these mRNA's from being translated into proteins.
What determines the type of protein that is produced in protein synthesis?
This could be answered a few ways, but at the most specific, it is the codons that are translated via tRNA which make a protein. Each codon, represented by 3 nucleotides, "codes" for an amino acid. A string of amino acids make a protein, thus the nucleotides in the codons determines the product. To get to this point, requires transcription from DNA into mRNA and then mRNA is translated into the amino acids, so you could say that DNA itself determines the protein produced; however, it is actually the codons in the mRNA that are used to make the protein. The section of DNA that is transcribed is called a gene, so you could also say that it is the gene that determines what is produced.
Which molecule determines the sequence of amino acids in a protein?
At the heart of it, DNA is the molecule that codes for the sequence of amino acids. DNA does this somewhat indirectly because its code is transcribed to mRNA, whose codons pair with specific tRNA anticodons, which are associated with a specific amino acid.
Do amino acids bind directly to the mRNA?
mRNA connects with the subunits of the ribosome. Each codon is read specifically and a matching anticodon brought by a tRNA is transferred. Each matched triplet adds amino acids to the polypeptide chain.
Where do Ribosomes bind on mRNA?
On the GGAGG sequence.
What is the nucleiotide sequence in mRNA that determines a specific amino acid?
groups of three nuleotides in mRNA codes for each one specific amino acid, these groups of three nucleotides are called as codon
What determines the sequence of bases in mRNA?
the sequence of bases in DNA
Haw does antisense technology work?
Antisense technology is based on stopping the production of a protein. In order for a protein to be formed, the mRNA has to be translated (read by the ribosomes). The happens in the cytoplasm. There are stretches of nucleic acid bases called cDNA that are complimentary to specific mRNA sequences. These cDNA molecules can bind to the mRNA molecules and inactivate them. When mRNA is inactivated, it cannot be translated into a protein and a protein will not be formed. Since every protein is made by a certain mRNA, by inactivating the mRNA using cDNA molecules, the production of the protein can be stopped. This process is called mRNA silencing or antisense technology
Where will the miRNA goes and binds?
MiRNA will leave the nucleus and bind to the 3'UTR of mRNA in the cytoplasm.
What is the sequence of events in translation?
1 ribosomes bind to mRNA 2 Amino acid-carrying tRNA molecules bind to mRNA 3 the polypeptide elongates as new amino acids are added 4 a stop codon on the mRNA is reached 5 the polypeptide is released 6 the ribosomes dissociate from the mRNA plato=C
How do hormones produce their effects?
Steroid hormones diffuse into cells being lipid-soluable and may enter any cell in the body. They bind a specific protein molecule - the receptor. This activates mRNA transcription.
How Steroid hormones produce their effects?
Steroid hormones diffuse into cells being lipid-soluable and may enter any cell in the body. They bind a specific protein molecule - the receptor. This activates mRNA transcription.
What is anti sense therapy?
Anti-sense therapy refers to inserting cDNA sequences to bind mRNA's (through complementarity thus preventing these mRNA's from being translated into proteins.
What determines the type of protein that is produced in protein synthesis?
This could be answered a few ways, but at the most specific, it is the codons that are translated via tRNA which make a protein. Each codon, represented by 3 nucleotides, "codes" for an amino acid. A string of amino acids make a protein, thus the nucleotides in the codons determines the product. To get to this point, requires transcription from DNA into mRNA and then mRNA is translated into the amino acids, so you could say that DNA itself determines the protein produced; however, it is actually the codons in the mRNA that are used to make the protein. The section of DNA that is transcribed is called a gene, so you could also say that it is the gene that determines what is produced.
What determines the mRNA sequence?
The genetic code is determined by the specific sequence of four nucleotide bases that make up DNA. The bases are guanine, adenine, thymine, and cytosine.
Which molecule determines the sequence of amino acids in a protein?
At the heart of it, DNA is the molecule that codes for the sequence of amino acids. DNA does this somewhat indirectly because its code is transcribed to mRNA, whose codons pair with specific tRNA anticodons, which are associated with a specific amino acid.
