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If it occurs suddenly, for no reason, it may be a neurological issue which could be caused by anything; an abscessed tooth, HSV/HZV infection, multiple sclerosis, or some other sort of viral or bacterial infection that has spread to the brain. All these could lead to what would actually cause the numbness: compression of a cranial nerve. Now, if your face is numb, and your eye, lip, or so on drooping (loss of facial muscle control) it is likely your Cranial Nerve 7. If it is just numb, and the facial muscle/movements are intact, then it is likely your Cranial Nerve 5.

*This info was Confirmed by a PCP (internal medicine), and a neurologist.

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Related Questions

What causes your forearms and thumb and forefinger to go numb at night?

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