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What molecule is involved in cell mediated cytotoxicity?

t cells


What is cytotoxicity?

Cytotoxicity refers to the ability of a substance to cause cell damage or death. It is often used in the context of evaluating the toxic effects of drugs, chemicals, or other agents on cells in laboratory settings. Cytotoxicity can impact various cellular processes and is an important consideration in fields such as toxicology and pharmacology.


What has the author Frank A Barile written?

Frank A. Barile has written: 'Introduction to in vitro cytotoxicology' -- subject(s): Cell culture, Cell-mediated cytotoxicity, In vitro, Toxicity testing 'Principles of Toxicology Testing'


How are cytotoxicity, sensitization, and irritation tests performed?

illillillill


What is the medical term meaning poisoning of cells?

Sepsis is about the most general term for poising of the cells. But "poisoning of the cells" is never a diagnosis because everything is essentially a cell. You would have to be more specific about which cells where being poisoned. However, in the strictist etymologic sense, cytotoxicity parses to "cell poisoning."


What has the author Jen-Nie Hu written?

Jen-Nie Hu has written: 'Natural killer cell activity and antibody-dependent cellular cytotoxicity of cats' -- subject(s): Cats, Diseases, Immunological aspects, Immunological aspects of Tumors, Tumor antigens, Tumors


What has the author Frances Elizabeth Bishop written?

Frances Elizabeth Bishop has written: 'Study of the metabolism and cytotoxicity of the ether lipid SRI 62-834'


How does Neutral red assay enters a cell?

Viable cells will take up the dye by active transport and incorporate the dye into lysosomes, whereas non-viable cells will not take up the dye. After the cells have been allowed to incorporate the dye they are briefly washed or fixed. The incorporated dye is then liberated from the cells in an acidified ethanol solution. An increase or decrease in the number of cells or their physiological state results in a concomitant change in the amount of dye incorporated by the cells in the culture. This indicates the degree of cytotoxicity caused by the test material.


What does MTT represent in MTT assay?

MTT represents "3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide," which is a yellow tetrazolium dye commonly used in cell viability assays. Its reduction by viable cells to purple formazan crystals helps measure cell proliferation and cytotoxicity.


What are the steps in cell mediated immune process?

Antigen presentation: Antigen-presenting cells (APCs) process and present antigens to T cells. T cell activation: APCs activate T cells by binding to their T cell receptors and providing co-stimulatory signals. T cell proliferation and differentiation: Activated T cells undergo clonal expansion and differentiate into effector T cells, such as cytotoxic T cells and helper T cells. Target cell destruction: Effector T cells recognize and kill infected or abnormal cells through various mechanisms, such as releasing cytotoxic molecules or activating other immune cells.


Are Viral infections are generally cytotoxic?

Viral infections can be cytotoxic, but the extent of cytotoxicity varies depending on the virus and the host's immune response. Some viruses directly kill host cells by disrupting cellular functions or triggering apoptosis, while others may cause damage indirectly by eliciting an immune response that harms nearby cells. Additionally, certain viral infections can lead to chronic conditions without immediate cytotoxic effects. Overall, the cytotoxicity of a viral infection is context-dependent.


Cytotoxic T cells can destroy cancer cells by means of a secretion called?

Cytotoxic T cells can destroy cancer cells by means of a secretion called perforin. Perforin is a protein that forms pores in the membrane of target cells, allowing toxic enzymes to enter and induce cell death.