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What is hybridoma?

Updated: 8/11/2023
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15y ago

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a hybrid cell formed by the fusion of a myeloma cell and an antibody-producing cell. Hybridomas are used to produce monoclonal antibodies.

Mosby's Medical Dictionary, 8th edition. © 2009, Elsevier.

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11y ago
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15y ago

a cell produced through genetic engineering by fusing an antibody-secreting lymphocyte cell and a non-antibody screting cell such as a myeloma (cancer) cell

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What are the disadvantages of the hybridoma technique?

Takes a long time, several weeks or months to create the hybridoma cells. Also costs a lot of money, and need to house and feed the mammal hosts for a long time while you immunize them


Definition of hybrydoma technology?

The correct spelling is hybridoma. The definition of hybridoma technology is a technology of forming hybrid cell lines that are called hybridmomas. Anti-body B cells with a myeloma cell are fused to form the cell lines.


What has the author Tanya Karns written?

Tanya Karns has written: 'The behaviour of hybridoma cells in culture'


Different types of fusion technique used in hybridoma technique?

The different types of fusion technique used in Hybridoma formatio are: 1. fusion mediated by PEG. 2. fusion mediated by DMSO. 3. Electrofusion 4. Viral Transformation (viral mediated fusion) using EB Virus, Sandai Virus.


How can you use antibodies to help you locate FSH-responsive cells?

In order to produce a monoclonal antibody against follicle stimulating hormone (FSH) a B cell capable of producing antibodies against FSH is fused with a myeloma cell. The resulting hybridoma is propagated, and an antibody produced by the hybridoma harvested. The antibody-producing hybridoma is detected utilising a radioimmunoassay together with immunohistology, and the fused cell hybrid selected is subsequently cloned into individual antibody-producing cell lines. In order to purify FSH impure FSH is passed through the monoclonal antibody against FSH bound to a matrix and the captured FSH is eluted from the matrix.


What has the author MaryLynne D Filaccio written?

MaryLynne D Filaccio has written: 'The effect of mitogen stimulated lymphocytes on fusion frequency in human hybridoma production' -- subject(s): Hybridomas, Interleukin-2, Microbiology, Biological response modifiers


How monoclonal antibody are produced?

by the help of hybridoma technology. single type of B cell which is sensitized with single epitope of antigen fysed with a myeloma cell. then that fused cell produce single type of antibody....that is monoclonal antibody.....


What are some nine letter words with 2nd letter Y and 6th letter D and 9th letter A?

According to SOWPODS (the combination of Scrabble dictionaries used around the world) there are 3 words with the pattern -Y---D--A. That is, nine letter words with 2nd letter Y and 6th letter D and 9th letter A. In alphabetical order, they are: hybridoma myxoedema synandria


What are some nine letter words with 1st letter H and 4th letter R and 5th letter I and 9th letter A?

According to SOWPODS (the combination of Scrabble dictionaries used around the world) there are 1 words with the pattern H--RI---A. That is, nine letter words with 1st letter H and 4th letter R and 5th letter I and 9th letter A. In alphabetical order, they are: hybridoma


What are some nine letter words with 1st letter H and 8th letter M and 9th letter A?

According to SOWPODS (the combination of Scrabble dictionaries used around the world) there are 5 words with the pattern H------MA. That is, nine letter words with 1st letter H and 8th letter M and 9th letter A. In alphabetical order, they are: haematoma hyalonema hybridoma hydrosoma hypoderma


What are some nine letter words with 1st letter H and 2nd letter Y and 3rd letter B and 9th letter A?

According to SOWPODS (the combination of Scrabble dictionaries used around the world) there are 1 words with the pattern HYB-----A. That is, nine letter words with 1st letter H and 2nd letter Y and 3rd letter B and 9th letter A. In alphabetical order, they are: hybridoma


What are some nine letter words with 4th letter R and 6th letter D and 8th letter M?

According to SOWPODS (the combination of Scrabble dictionaries used around the world) there are 6 words with the pattern ---R-D-M-. That is, nine letter words with 4th letter R and 6th letter D and 8th letter M. In alphabetical order, they are: astrodome clerkdoms fairydoms hybridoma macrodome whoredoms