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1. An antigen presenting cell presents antigen on Class II MHC to a Helper T cell activating it

2. At the same time a B cell that has taken up and degraded the same pathogen displays antigen on its class II

3. The activated helper T cell binds to the B cell releasing cytokines and activating it

4. The activated B cell proliferates and differentiates into:

1) memory B cells

2) antibody-secreting plasma cells that produce antibodies specific for the

pathogen

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define clonal selection therory?

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Q: What is the clonal selection theory as it applies to B cells?
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What is clonal selection responsible for?

Clonal selection is responsible for the proliferation of clones of effector and memory cells specific for an encountered antigen


Antigen presentation is essential for the activation and clonal selection of?

T cells


What does the Clonal Selection Theory state?

The Clonal Selection Theory explain how the immune system can be both diverse and very specific at the same time.The theory states:All antibodies are precommitted to making a single antibody with a single specificityA single cell produces only one antibody which interacts with only one antigen with the highest specificityWhen the right antigen interacts with that cell, it leads to clonal expansion and proliferation of that cell, so that many daughter-cells are made with the exact same specificityThe ability to recognise an antigen is dependent on a receptor, and the receptor is a product of the same cell that secretes the antibody. This ensures that made antibodies will fit with the antigen they are supposed to bind.A clone is defined as a group of cells in which all daughter cells are equal in their specificity


Which cells exhibit clonal diversity?

Human cells that exhibit clonal diversity are the T and B lymphocytes which are important cells of the immune response.


What cells produce antibody?

T plasma cells, if your at A level or anything lower, you don't need to write anymore than that. T plasma cells are formed through clonal selection.


In clonal selection of b cells which substance is responsible for determining which cells will eventually become cloned?

there are 100,000 antibodies on the surface of b-cells which are specific for particular type of antigen therefore if specific antibody recognize the particular type antigen then it attach with it and activated.


What process provides many b cells and t cells that are activated against specific antigens?

Clonal expansion is the process that provides many B cells and T cells that are activated against specific antigens. Clonal expansion is what provides the immune system its strength.


What is clonal propagation?

Clonal proliferation is the concept of daughter cells arising from one cell originally. This means they all share the same antigen specificity.


What is selection of multiple cells called?

A selection of multiple cells is oftenreferredto as a range.


What type of cells does the cell theory apply to?

every single living organism with cells, so the cell theory, which states what classifies something as a cell, applies to all cells.note: viruses are not alivenote: slime molds such as Physarum polysephalum are acellular.


What is the ability of a specific immune cell to proliferate and form many generations of nearly identical cells called?

The ability of a specific immune cell to proliferate and form many generations of nearly identical cells is called clonal expansion. During clonal expansion, activated immune cells undergo multiple rounds of cell division, resulting in the production of numerous identical daughter cells that can mount a coordinated immune response against the targeted pathogen or antigen.


Which component of the cell theory discredited the theory of spontaneous generation?

Cells come from other cells.