1. An antigen presenting cell presents antigen on Class II MHC to a Helper T cell activating it
2. At the same time a B cell that has taken up and degraded the same pathogen displays antigen on its class II
3. The activated helper T cell binds to the B cell releasing cytokines and activating it
4. The activated B cell proliferates and differentiates into:
1) memory B cells
2) antibody-secreting plasma cells that produce antibodies specific for the
pathogen
define clonal selection therory?
Clonal selection is responsible for the proliferation of clones of effector and memory cells specific for an encountered antigen
T cells
Clonal proliferation is the concept of daughter cells arising from one cell originally. This means they all share the same antigen specificity.
every single living organism with cells, so the cell theory, which states what classifies something as a cell, applies to all cells.note: viruses are not alivenote: slime molds such as Physarum polysephalum are acellular.
This is one of the three ideas in the "Cell theory".
Clonal selection is responsible for the proliferation of clones of effector and memory cells specific for an encountered antigen
T cells
The Clonal Selection Theory explain how the immune system can be both diverse and very specific at the same time.The theory states:All antibodies are precommitted to making a single antibody with a single specificityA single cell produces only one antibody which interacts with only one antigen with the highest specificityWhen the right antigen interacts with that cell, it leads to clonal expansion and proliferation of that cell, so that many daughter-cells are made with the exact same specificityThe ability to recognise an antigen is dependent on a receptor, and the receptor is a product of the same cell that secretes the antibody. This ensures that made antibodies will fit with the antigen they are supposed to bind.A clone is defined as a group of cells in which all daughter cells are equal in their specificity
Human cells that exhibit clonal diversity are the T and B lymphocytes which are important cells of the immune response.
T plasma cells, if your at A level or anything lower, you don't need to write anymore than that. T plasma cells are formed through clonal selection.
there are 100,000 antibodies on the surface of b-cells which are specific for particular type of antigen therefore if specific antibody recognize the particular type antigen then it attach with it and activated.
Clonal expansion is the process that provides many B cells and T cells that are activated against specific antigens. Clonal expansion is what provides the immune system its strength.
Clonal proliferation is the concept of daughter cells arising from one cell originally. This means they all share the same antigen specificity.
A selection of multiple cells is oftenreferredto as a range.
every single living organism with cells, so the cell theory, which states what classifies something as a cell, applies to all cells.note: viruses are not alivenote: slime molds such as Physarum polysephalum are acellular.
The ability of a specific immune cell to proliferate and form many generations of nearly identical cells is called clonal expansion. During clonal expansion, activated immune cells undergo multiple rounds of cell division, resulting in the production of numerous identical daughter cells that can mount a coordinated immune response against the targeted pathogen or antigen.
Cells come from other cells.