1. An antigen presenting cell presents antigen on Class II MHC to a Helper T cell activating it
2. At the same time a B cell that has taken up and degraded the same pathogen displays antigen on its class II
3. The activated helper T cell binds to the B cell releasing cytokines and activating it
4. The activated B cell proliferates and differentiates into:
1) memory B cells
2) antibody-secreting plasma cells that produce antibodies specific for the
pathogen
Clonal selection theory explains how the adaptive immune system selects and amplifies immune cells (such as B cells and T cells) that are specific to antigens. When a pathogen enters the body, immune cells with receptors that match the antigen are selected for activation and proliferation, leading to a targeted immune response. This theory is fundamental to understanding how the immune system responds to infections and develops immunological memory.
Antigen-presenting cells (APCs) are nonlymphocyte cells that play a central role in clonal selection. They present antigens to T cells, triggering the immune response and selection of specific clones of T cells that can recognize and respond to the antigen.
Clonal selection is responsible for the production of a large population of identical B or T cells that specifically recognize and target a particular antigen. This process is critical for the adaptive immune system's ability to mount a targeted immune response against pathogens.
Antigen challenge and clonal selection are most likely to occur in the secondary lymphoid organs, such as the lymph nodes and spleen. These organs are where antigens encounter immune cells, triggering an immune response and the selection of specific immune cell clones.
T cells. Antigen-presenting cells (APCs) process and present antigens to T cells, initiating an immune response. This interaction is crucial for the adaptive immune system to recognize and combat pathogens or abnormal cells.
Clonal selection theory explains how the adaptive immune system selects and amplifies immune cells (such as B cells and T cells) that are specific to antigens. When a pathogen enters the body, immune cells with receptors that match the antigen are selected for activation and proliferation, leading to a targeted immune response. This theory is fundamental to understanding how the immune system responds to infections and develops immunological memory.
Antigen-presenting cells (APCs) are nonlymphocyte cells that play a central role in clonal selection. They present antigens to T cells, triggering the immune response and selection of specific clones of T cells that can recognize and respond to the antigen.
Clonal selection is responsible for the production of a large population of identical B or T cells that specifically recognize and target a particular antigen. This process is critical for the adaptive immune system's ability to mount a targeted immune response against pathogens.
The Clonal Selection Theory explain how the immune system can be both diverse and very specific at the same time.The theory states:All antibodies are precommitted to making a single antibody with a single specificityA single cell produces only one antibody which interacts with only one antigen with the highest specificityWhen the right antigen interacts with that cell, it leads to clonal expansion and proliferation of that cell, so that many daughter-cells are made with the exact same specificityThe ability to recognise an antigen is dependent on a receptor, and the receptor is a product of the same cell that secretes the antibody. This ensures that made antibodies will fit with the antigen they are supposed to bind.A clone is defined as a group of cells in which all daughter cells are equal in their specificity
Antigen challenge and clonal selection are most likely to occur in the secondary lymphoid organs, such as the lymph nodes and spleen. These organs are where antigens encounter immune cells, triggering an immune response and the selection of specific immune cell clones.
The process of clonal selection in the immune system produces numerous B cells and T cells that are activated in response to specific antigens. This involves the proliferation of cells that have receptors capable of binding to a particular antigen, resulting in an amplified response to combat the invading pathogen.
Cells of the immune system, such as B cells and T cells, exhibit clonal diversity. They undergo rearrangement of their antigen receptor genes to generate a diverse repertoire of cells capable of recognizing a wide range of antigens. This clonal diversity allows the immune system to respond to a variety of pathogens and antigens.
T plasma cells, if your at A level or anything lower, you don't need to write anymore than that. T plasma cells are formed through clonal selection.
T cells. Antigen-presenting cells (APCs) process and present antigens to T cells, initiating an immune response. This interaction is crucial for the adaptive immune system to recognize and combat pathogens or abnormal cells.
there are 100,000 antibodies on the surface of b-cells which are specific for particular type of antigen therefore if specific antibody recognize the particular type antigen then it attach with it and activated.
Clonal expansion is the proliferation of a single cell or a group of genetically identical cells within a population. This process is crucial in immune responses, where specific immune cells multiply to combat a pathogen. Clonal expansion is also important in the development of cancer, where a single mutated cell replicates uncontrollably to form a tumor.
every single living organism with cells, so the cell theory, which states what classifies something as a cell, applies to all cells.note: viruses are not alivenote: slime molds such as Physarum polysephalum are acellular.